Source: Annual Congress 2008 - Lung and bone marrow transplantation: miscellaneous

Abstract

Airway stenoses cause morbidity and mortality in lung transplant recipients. When recurrend balloon dilatations is not sufficient temporary stent placement is a treatment option. Removability is one of the required stent properties in this situation. The new fully covered Nitinol device Aero (Alveolus, USA) might comply with the requirements in airway stenoses after lung transplantation
In this study we evaluated the efficacy, safety and handling of a new airway stent in bronchial stenoses after lung transplantation.
Seven lung transplant recipients (cystic fibrosis n=3, fibrosis n=2, emphysema n=2) underwent stent placement (11 stents) using a new fully covered hybrid device (AERO-stent, Alveolus). Stent implantation was done under bronchoscopic and fluoroscopic control over the guidewire.
Deployment of the stents was successful in all cases providing excellent airway patency immediately. There was no procedural related complication. Clinical findings and lung function improved markedly in 6 patients. We observed relevant granulation formation in one patient. Two stents migrated distally within hours. One of them was replaced, the other one removed. The remaining stents have been removed after an interval between 35 and 103 days without difficulties.
The fully covered metallic stent proved efficient, easy to implant and easy to remove in this study. We conclude, that this device deserves further evaluation in temporary stenting of airway stenoses after lung transplantation.

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B. Schmidt, H. Lehmkuhl, L. Hanitsch, C. Knosalla, D. Kemper, R. Hetzer, C. Witt (Berlin, Germany). Treating post transplantation airway stenoses with a fully covered metallic stent. Eur Respir J 2008; 32: Suppl. 52, 1630

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