Inhaled budesonide causes rapid vasoconstriction in the isolated and perfused rat lung

P. Ewing, C. O. Sjöberg, P. Andersson, S. Edsbäcker, A. Ryrfeldt, P. Gerde (Lund, Stockholm, Sweden)

Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD
Session: Novel experimental approaches to understanding asthma and COPD
Session type: Thematic Poster Session
Number: 3652
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
P. Ewing, C. O. Sjöberg, P. Andersson, S. Edsbäcker, A. Ryrfeldt, P. Gerde (Lund, Stockholm, Sweden). Inhaled budesonide causes rapid vasoconstriction in the isolated and perfused rat lung. Eur Respir J 2008; 32: Suppl. 52, 3652

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Inhaled endothelin-receptor-blockers in acute pulmonary hypertension in an isolated ventilated and buffer perfused rabbit lung model
Source: Eur Respir J 2006; 28: Suppl. 50, 427s
Year: 2006

A novel tool for the assessment of pulmonary disposition of dry powder aerosols; the isolated and perfused rat lung exposed to budesonide, formoterol and terbutaline
Source: Eur Respir J 2007; 30: Suppl. 51, 352s
Year: 2007

Acute increase in pulmonary blood flow elevates airway responsiveness in isolated perfused rat lungs
Source: Annual Congress 2008 - Respiratory pathophysiology from cell and animal research
Year: 2008



Sustained PAP-reduction and tissue cGMP-restoration without systemic NO-generation by aerosolized PAPA-NONOate in an isolated lung model of acute lung injury
Source: Eur Respir J 2004; 24: Suppl. 48, 561s
Year: 2004

Non linear kinetics of absorption of inhaled Benso(a)Pyrene in the isolated perfused and ventilated rat lung
Source: Eur Respir J 2005; 26: Suppl. 49, 151s
Year: 2005

Inhaled sodium nitrite attenuates hypoxic pulmonary vasoconstriction
Source: Annual Congress 2008 - Pulmonary vascular biology
Year: 2008

Sustained alveolar hypoxia provokes biphasic vasoconstriction and loss of post-hypoxic vasorelaxation in isolated rabbit lungs
Source: Eur Respir J 2001; 18: Suppl. 33, 414s
Year: 2001

Features of hypoxic pulmonary vasoconstriction in isolated perfused and ventilated mice lungs
Source: Eur Respir J 2003; 22: Suppl. 45, 270s
Year: 2003

Inhaled nitric oxide increases alveolar liquid clearance in rabbit with endotoxin induced lung injury
Source: Eur Respir J 2004; 24: Suppl. 48, 101s
Year: 2004

Relationship between the inhaled and pulmonary absorbed dose of budesonide and mometasone furoate: A study in the isolated perfused rat lung
Source: Annual Congress 2010 - Drug delivery and pharmacokinetics II
Year: 2010

Inhaled liposomal iloprost extend detectable plasma level and prolong reduction of hypoxia-induced pulmonary hypertension in rat
Source: International Congress 2019 – Pulmonary hypertension with lung diseases and experimental pulmonary hypertension
Year: 2019

Inhaled racemic salbutamol may cause enhanced bronchial response to cold air in mild asthmatics
Source: Eur Respir J 2001; 18: Suppl. 33, 105s
Year: 2001

Inhaled vasodilators in acute lung injury
Source: ISSN=1025-448x, ISBN=1-904097-23-5, page=129
Year: 2002

Effects of Sildenafil on hypoxic pulmonary vasoconstriction in dogs
Source: Eur Respir J 2001; 18: Suppl. 33, 490s
Year: 2001

Rapid inhibitory effects of budesonide and formoterol on bradykinin-induced Ca2+ mobilization in human lung fibroblasts
Source: Annual Congress 2010 - Regulation of airway pharmacology
Year: 2010

Sildenafil enhances the pulmonary vasodilatory response to inhaled iloprost in experimental pulmonary hypertension
Source: Eur Respir J 2002; 20: Suppl. 38, 24s
Year: 2002

Inhaled iloprost reverses chronic experimental pulmonary hypertension
Source: Eur Respir J 2005; 26: Suppl. 49, 353s
Year: 2005

Effects of salbutamol enantiomers on equine isolated bronchial airways
Source: Annual Congress 2009 - Models of chronic airways disease and therapy
Year: 2009

Relaxin potentiates ß2-adrenoceptor mediated bronchodilation in precision-cut lung slices (PCLS) from mouse models of airway inflammation and fibrosis, and in human airways
Source: International Congress 2019 – Advances in asthma pharmacology
Year: 2019

The mediators of allergen-induced bronchoconstriction in the isolated perfused and ventilated guinea pig lung (IPL) are closely similar to those in asthmatics
Source: Eur Respir J 2003; 22: Suppl. 45, 104s
Year: 2003