Reduced numbers of circulating CD4+CD25highFOXP3+ regulatory T cells in patients with allergic asthma

S. Provoost, Y. van Durme, G. F. Joos, T. Maes, K. G. Tournoy (Ghent, Belgium)

Source: Annual Congress 2008 - Understanding airway inflammation
Session: Understanding airway inflammation
Session type: E-Communication Session
Number: 4453
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
S. Provoost, Y. van Durme, G. F. Joos, T. Maes, K. G. Tournoy (Ghent, Belgium). Reduced numbers of circulating CD4+CD25highFOXP3+ regulatory T cells in patients with allergic asthma. Eur Respir J 2008; 32: Suppl. 52, 4453

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
T regulatory cells decrease before asthma exacerbations
Source: Annual Congress 2008 - Understanding the mechanisms and the impact of severe asthma
Year: 2008

Low number of regulatory T cells in bronchial asthma: association with inflammatory cytokines
Source: Annual Congress 2009 - Infections, immunity and inflammation
Year: 2009



Increased levels of CD4+CD25high and CD4+FoxP3+ T-regulatory cells (Tregs) in patients with different severity of bronchial asthma (BA)
Source: Annual Congress 2011 - Immunology and cell biology of asthma and COPD
Year: 2011

Expression of surface markers on peripheral CD4+CD25high T cells in patients with atopic asthma: role of inhaled corticosteroid
Source: Annual Congress 2008 - Risk factors for asthma versus asthma control
Year: 2008

Effects of depletion of CD4+CD25+ T cells with anti-CD25McAb on airway inflammation of asthmatic mice
Source: Eur Respir J 2005; 26: Suppl. 49, 24s
Year: 2005

Activin-A induces human regulatory T cells that control allergic asthma
Source: Annual Congress 2012 - Asthma and COPD: understanding through mechanisms
Year: 2012

T-regulatory cells blood content in patients with asthma exacerbation
Source: Annual Congress 2011 - T-cell subsets
Year: 2011


Increase of both blood CXCR3+ and CCR4+ helper T cells associated with severity of asthma
Source: Annual Congress 2005 - Inflammation and remodelling in allergy and asthma
Year: 2005


Omalizumab enhances the percentage of GARP cells in both regulatory and terminally differentiated effector Th cells in severe allergic asthmatics
Source: International Congress 2018 – Novel immunology-based therapies in asthma and COPD
Year: 2018



Reduced bronchial CD4+ T cell activation in smokers with occupational asthma
Source: Eur Respir J 2006; 28: Suppl. 50, 592s
Year: 2006

The role of regulatory T cells in differentiating asthma from COPD
Source: Eur Respir J 2007; 30: Suppl. 51, 373s
Year: 2007

Different profiles of lung and systemic regulatory T cells in mild asthmatics
Source: Annual Congress 2010 - COPD and asthma: models and human studies
Year: 2010


Enhanced expression of IL-18 and increased CD8+ T cells and eosinophils in the airways of asthma death
Source: Annual Congress 2010 - Mechanisms of asthma and lung inflammation
Year: 2010


CD39/CD73 and the imbalance of Th17 and Tregs (regulatory T cells) in allergic asthma
Source: Annual Congress 2013 –Studies of asthma in man
Year: 2013

Diminished levels of IL-7 receptor-positive CD4+ T cells in asthmatic patients are up-regulated by glucocorticoid therapy. No effects on IL-7R-negative regulatory CD4+ T cells
Source: Annual Congress 2010 - Mechanisms of asthma and lung inflammation
Year: 2010


Comparative characteristics of regulatory T cells populations between patients with bronchial asthma (BA) and COPD
Source: Annual Congress 2011 - T-cell subsets
Year: 2011

The declined CD4+ CD25+Treg cells in patients with moderate to severe asthma associated with over-expressed Th2 response
Source: Annual Congress 2012 - Asthma and COPD: understanding through mechanisms
Year: 2012

IL-10-producing CD4+ T cells are essential for the development of airway hyperresponsiveness
Source: Annual Congress 2004 - Modulation of the allergic response in animal models
Year: 2004


Regulatory T cells and L-selectin in severe asthmatic patients treated with mepolizumab.
Source: Virtual Congress 2020 – Personalised treatment of obstructive diseases
Year: 2020


Upregulation of CD4+ and CD8+ cells expressing CX3CR1 in asthmatics
Source: Annual Congress 2006 - Towards understanding the pathogenesis of asthma
Year: 2006