Monitoring T-cell immunity towards M. tuberculosis: impaired specific immunocompetence in patients receiving high levels of immunosuppressive drugs

U. Sester, H. Wilkens, U. Mack, G. W. Sybrecht, M. Sester (Homburg, Germany)

Source: Annual Congress 2008 - Genetics, immunology and microbiology of tuberculosis
Session: Genetics, immunology and microbiology of tuberculosis
Session type: E-Communication Session
Number: 4522
Disease area: Respiratory infections

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Citations should be made in the following way:
U. Sester, H. Wilkens, U. Mack, G. W. Sybrecht, M. Sester (Homburg, Germany). Monitoring T-cell immunity towards M. tuberculosis: impaired specific immunocompetence in patients receiving high levels of immunosuppressive drugs. Eur Respir J 2008; 32: Suppl. 52, 4522

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Member's Comments

Paul Kelly - 07.10.2008 10:10
P Kelly
That immunosupression - iatrogenic or due to disease - lowers the capability to react to TB is clear. Yo seem to argue that in vitro testing might be an alternative to skin testins but irrespective of which test is used what clinical impact does a positive result have ?

Massimo Amicosante - 04.10.2008 09:52
Bio-equivalent of calcineurin inhibitors concentration
very nice and extensive work. For providing a further indication to clinically oriented audience, could you please add information about the in vivo bioequivalance of the calcineurin inhibitors used for the in vitro experiments? and not only present the data obtained ex vivo after peak injection of cyclosporin A.
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