Matrix metalloproteinase 12 (MMP-12) expression in human monocyte-derived macrophages is enhanced by exposure to cigarette smoke and is resistant to suppression by dexamethasone Source: Eur Respir J 2004; 24: Suppl. 48, 107s Year: 2004
Potent anti-inflammatory effects of the highly selective iNOS inhibitor Byk402750 in a mouse model of cigarette smoke induced inflammation Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD Year: 2008
Cigarette smoke upregulates IL-8/CXCL8 expression by augmenting mRNA stability via p38 MAPK/MK2 signalling in normal human pulmonary cells Source: Annual Congress 2012 - Basic and translational studies in COPD Year: 2012
Cigarette smoke upregulating the expression of miR 21 increases IL-8 in airway epithelial cells Source: International Congress 2018 – New kids on the block: novel molecular pathways and therapeutic targets in chronic lung diseases Year: 2018
Comparison of the gene expression profile in lung fibroblasts from patients with emphysema and changes in gene expression induced by cigarette smoke extract (CSE) Source: Eur Respir J 2006; 28: Suppl. 50, 585s Year: 2006
Cilomilast, a second generation phosphodiestease 4 inhibitor, in combination with PGE2 attenuates fMLP, IL-8 and cigarette smoke-induced effects on the mechanical and functional properties of neutrophils Source: Eur Respir J 2001; 18: Suppl. 33, 161s Year: 2001
A selective MMP-12 inhibitor, MV062926, reduces inflammatory responses to cigarette smoke in mice Source: Annual Congress 2010 - Pre-clinical models of airways disease Year: 2010
Cigarette smoke extract (CSE) induces clusterin expression in human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 105s Year: 2004
Sildenafil and rolipram prevent pulmonary endothelial cells apoptosis and ANG-2 overexpression induced by cigarette smoke Source: Annual Congress 2008 - Pulmonary vascular biology Year: 2008
Cytosolic phospholipase A2 type IVβ induces interleukin – 8 and cyclooxygenase -2 gene expression but does not influence IL-16 and heme oxygenase-1 transcription in human lung cells Source: Annual Congress 2004 - Inflammation and remodelling in human lungs Year: 2004
Cigarette smoke enhances beta-defensin 2 expression in rat airways via nuclear factor-kappa-B activation Source: Eur Respir J 2010; 36: 638-645 Year: 2010
Cigarette smoking modulates double-stranded RNA-induced interleukin 6 release from bronchial epithelial cells by decreasing TLR-3 expression Source: Annual Congress 2007 - Immunological function in viral and nonviral pathogens Year: 2007
Involvement of MMP-12 and phosphodiesterase type 4 in cigarette smoke-induced inflammation in mice Source: Eur Respir J 2006; 27: 1102-1109 Year: 2006
Decreased expression of VEGF in the lungs of cigarettes smoke exposure mice Source: Eur Respir J 2003; 22: Suppl. 45, 434s Year: 2003
Cigarette smoke up-regulates toll like receptor 4 (TLR4) expression and enhances TLR4 mediated responses Source: Eur Respir J 2005; 26: Suppl. 49, 555s Year: 2005
Modification of NF-kappa B dependent Interleukin-8 expression via inhibition of histone deacetylation in human alveolar macrophages - effect of cigarette smoking Source: Eur Respir J 2002; 20: Suppl. 38, 87s Year: 2002
Overexpression of CBP augments cigarette smoke-induced pro-inflammatory cytokine release in macrophages Source: Eur Respir J 2005; 26: Suppl. 49, 105s Year: 2005
PDE4 inhibition prevents corticosteroid-resistant lung inflammation induced by cigarette smoke exposure in mice Source: Annual Congress 2009 - Highlighting the epithelial cell in lung disease: from COPD to cancer to acute lung injury Year: 2009
ERK MAP kinase is upregulated in pulmonary emphysema and mediates MMP-1 induction by cigarette smoke Source: Eur Respir J 2004; 24: Suppl. 48, 437s Year: 2004
Effect of cigarette smoke extract (CSE) on the adenosine receptor expression and degranulation of the human mast cell line 1 (HMC-1) Source: Annual Congress 2007 - Inflammatory cell biology Year: 2007