Bosentan blocks TNFα-induced GM-CSF expression in human airway smooth muscle cells

D. Jungck, H. Peters, K. Mueller, J. Strauch, J. Knobloch, A. Koch (Cologne, NRW, Germany)

Source: Annual Congress 2008 - Basic science in asthma and COPD
Session: Basic science in asthma and COPD
Session type: Thematic Poster Session
Number: 3569
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
D. Jungck, H. Peters, K. Mueller, J. Strauch, J. Knobloch, A. Koch (Cologne, NRW, Germany). Bosentan blocks TNFα-induced GM-CSF expression in human airway smooth muscle cells. Eur Respir J 2008; 32: Suppl. 52, 3569

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Eotaxin/CCL11 inhibits proliferation of human airway smooth muscle cells
Source: Eur Respir J 2005; 26: Suppl. 49, 127s
Year: 2005

Eotaxin and CCR3 expression in cultured human airway smooth muscle cells
Source: Eur Respir J 2002; 20: Suppl. 38, 2s
Year: 2002

Eosinophils promote airway smooth muscle cells contractility and a-actin gene expression in asthma
Source: International Congress 2018 – Identification of therapeutic targets for asthma
Year: 2018

Endothelin receptor B protects GM-CSF mRNA from degradation in human airway smooth muscle cells
Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects
Year: 2015

IL-1β-induced MCP-1 production in human airway smooth muscle cells, modulation by dexamethasone, rolipram, and salbutamol
Source: Eur Respir J 2001; 18: Suppl. 33, 353s
Year: 2001

Co-culture of human airway epithelial cells alter the proliferation of human airway smooth muscle cells
Source: Eur Respir J 2002; 20: Suppl. 38, 572s
Year: 2002

RNA interference decreases PAR-2 expression and function in human airway smooth muscle cells
Source: Eur Respir J 2005; 26: Suppl. 49, 128s
Year: 2005

Omalizumab inhibits IgE-induced cytokine secretion by human airway smooth muscle cells
Source: Annual Congress 2008 - Basic science in asthma and COPD
Year: 2008

Resveratrol impairs cytokine release from human airway smooth muscle cells (HASMCs) and alveolar macrophages (AM) in COPD
Source: Annual Congress 2009 - Models of chronic airways disease and therapy
Year: 2009

Role of corticosteroids in TNFα-induced expression of vascular endothelial growth factor (VEGF) in human airway smooth muscle cells
Source: Annual Congress 2003 - Cell signalling and cytokines in asthma
Year: 2003


Effects of bosentan, ambrisentan and TBC3711 on TNFα induced and endothelin-1 modulated gm-csf expression in human airway smooth muscle cells
Source: Annual Congress 2009 - Airway cell biology
Year: 2009


Tocotrienol inhibits TGF-beta1-induced human airway smooth muscle cell differentiation
Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Year: 2013


The effect of gamma-tocotrienol on human airway smooth muscle cell proliferation and migration
Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Year: 2013


Cytokines IL-4 and GM-CSF up regulate CD23 expression in human airway smooth muscle cells
Source: Eur Respir J 2004; 24: Suppl. 48, 38s
Year: 2004

Inhibition of IL-8 and RANTES release from cultured human airway smooth muscle cells by fluticasone and budesonide
Source: Eur Respir J 2002; 20: Suppl. 38, 384s
Year: 2002

Anti-inflammatory effect of bosentan on endothelin-1- and TNF-α-induced GMCSF expression in human airways smooth muscle cells – role of MAPkinases ERK-1,-2
Source: Annual Congress 2007 - Inflammatory cell biology
Year: 2007


Exogenous BMPR2 modulates TGF-β signalling in human small airway epithelium and smooth muscle cells
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and cell biology
Year: 2012

LSC Abstract – Eosinophils enhance WNT-5a and TGF-β1 genes expression in airway smooth muscle cells and promote their proliferation in asthma
Source: International Congress 2016 – Clinical characteristics of asthma
Year: 2016

Sphingosine-1-phosphate receptor expression and signalling in human airway smooth muscle cells
Source: Annual Congress 2011 - Airway smooth muscle cells and fibroblasts: cell biology
Year: 2011

Heme-oxygenase (HO)-1 inhibits TNF-α induced CXCL10 secretion by airway smooth muscle cells
Source: Annual Congress 2011 - Airway smooth muscle cells and fibroblasts: cell biology
Year: 2011