IFN γ tests for tuberculosis – false positives with other T cell disease processes?

J. Robson, N. Coulson, N. Haley, J. Anderson, H. Hosker (Keighley, West Yorkshire, United Kingdom)

Source: Annual Congress 2008 - Interferon-gamma methods for the diagnosis of tuberculosis infection and disease
Session: Interferon-gamma methods for the diagnosis of tuberculosis infection and disease
Session type: Oral Presentation
Number: 4581
Disease area: Respiratory infections

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
J. Robson, N. Coulson, N. Haley, J. Anderson, H. Hosker (Keighley, West Yorkshire, United Kingdom). IFN γ tests for tuberculosis – false positives with other T cell disease processes?. Eur Respir J 2008; 32: Suppl. 52, 4581

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
T cell and B cell immunological responses by tuberculous antigens in Japanese populations with different bacterial antigen expressions
Source: Annual Congress 2013 –Tuberculosis diagnosis
Year: 2013

IFN-γ T cell response in the diagnosis of latent tuberculosis infection in children with a positive tuberculin skin test
Source: Annual Congress 2009 - Tuberculosis contact screening
Year: 2009


Additional analysis of antigen-specific Interleukin-2 release does not improve the performance of IGRAs for the differentiation of different states of mycobacterium tuberculosis infection
Source: International Congress 2014 – Future frontiers in the diagnosis of Mycobacterium tuberculosis infection
Year: 2014


Our experience of T cell assays in the diagnosis of MTB disease and latent infection
Source: Annual Congress 2007 - Gamma-interferon-based tests to diagnose tuberculosis infection and disease
Year: 2007


Unfavorable factors associated with false negative results of interferon-gamma release assay for tuberculosis
Source: Annual Congress 2011 - Risk assessment for tuberculosis
Year: 2011


Comparison of effector T-cell responses in patients with active TB disease compared to latent TB infection
Source: Annual Congress 2007 - New perspectives and old problems in diagnosing tuberculosis infection and disease
Year: 2007



The value of interferon-gamma releasing assays (IGRA) determining latent tuberculosis infection in renal transplant candidates
Source: International Congress 2016 – Active and latent tuberculosis: biomarkers
Year: 2016


Unique cytokine profiles of CD4+T cell to Acr, HBHA and MDP-1 antigens in different clinical stage of mycobacterium tuberculosis infection
Source: International Congress 2014 – Future frontiers in the diagnosis of Mycobacterium tuberculosis infection
Year: 2014

IFN-gamma response on T-cell based assays in HIV patients for detection of tuberculosis infection
Source: Annual Congress 2008 - New methods to diagnose tuberculosis infection and disease
Year: 2008

Tuberculin skin test or interferon gamma release assay - How to detect latent tuberculosis infection in sarcoidosis patients?
Source: International Congress 2015 – Sarcoidosis: clinical
Year: 2015

Are there any similarities between the skin and the blood tests with CFP10-ESAT6 in tuberculosis patients?
Source: Annual Congress 2013 –Diagnostic features of tuberculosis II
Year: 2013

Paradoxical reactions (PR) related to tuberculosis (TB) treatment are associated with increased antigen-specific T cell responses in the lung
Source: Annual Congress 2009 - Tuberculosis and HIV co-infection
Year: 2009


A combinatorial dual-immunoassay predicts reactivation risk for patients with previously incomplete treatment for latent tuberculosis infection
Source: International Congress 2016 – Active and latent tuberculosis: biomarkers
Year: 2016


Can we predict who will develop TB among those with a positive interferon-? release assay (IGRA)?
Source: International Congress 2018 – Important changes in the management of tuberculosis
Year: 2018


Evaluation of the accuracy of several immune experimental diagnostic tools to distinguish active tuberculosis from latent infection
Source: International Congress 2015 – Science and biomarkers in TB
Year: 2015

Correlation of Mycobacterium tuberculosis [not]-specific and non-specific quantitative T cell IFN-γ responses with mycobacillary load in a HIV-prevalent high burden setting
Source: Annual Congress 2012 - Prognostic indices in respiratory infections
Year: 2012


Tuberculin skin testing to the IGRA positive contacts of infectious tuberculosis cases for the treatment of latent tuberculosis infection
Source: International Congress 2015 – Latent TB infection and screening
Year: 2015


The value of interferon (IFN)-γ blood tests in diagnosis of tuberculosis
Source: Annual Congress 2007 - Gamma-interferon-based tests to diagnose tuberculosis infection and disease
Year: 2007


Residual DNA of Mtb from the bronchoscope channel as a possible cause of false positive results in the diagnosis of tuberculosis
Source: Virtual Congress 2021 – Advances in the diagnosis of tuberculosis, multidrug-resistant tuberculosis and nontuberculous mycobacterial disease
Year: 2021



The role of increasing TIM3 on T cells in patients with nontuberculous mycobacterial lung disease: from immune cell dysfunction to clinical severity
Source: Virtual Congress 2021 – Advances in the diagnosis of tuberculosis, multidrug-resistant tuberculosis and nontuberculous mycobacterial disease
Year: 2021