Source: Annual Congress 2008 - Mediastinal lesions; rare pathology
Disease area: Thoracic oncology

Abstract

Objectives : cervico – medistinal goiter, part of the outlet syndrome, could be the source for many diagnosis and therapeutic difficulties.
Materials and methods : In this retrospective study of 18 patients with cervico-mediastinal goiter treated by surgical resection between 1997 and 2007 we assessed clinical features, radiologic and imagistic findings, levels of tyroid hormons (T3/T4) and postoperative outcomes.
Results : mean age was 42 years (+/- 5 years), male /female : 5/13. Clinical features : increased consistency cervical edema 5 cases (27.77%), mediastinal compression in 13 cases (72.22%) : dysphonia, dyspnea, increased jugular vein pressure. Localization : prevascular cervico-mediastinal goiter in 7 cases (38.88%), retrovascular and pretracheal cervico-mediastinal goiter in 8 (44.44 %) laterally from trachea and oesophagus in 3 cases (16.66%). In 12 (66.66%) cases we used a cervical approach, and in 6 (33.33%) cases a combined cervical with partial sternotomy approach. In 11 cases (61.11%) we made a complete tyroidectomy, 3 cases (16.66 %) right lobectomy with resection of thyroid istm and left lobectomy in 4 cases (22.22). Postoperative complications: temporary unilateral recurrent disfunction 4 cases (22.22%) and transient hypoparathyroidism in 3 cases (16.66%)
Conclusion : despite to large variety of clinical features, surgical resection of cervico-mediastinal goiter associated with postoperative hormone therapy offered the best outcomes.

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Citations should be made in the following way:
N. Galie, B. Stanescu, E. Crisan, E. Tabacu, V. Grigorie (Bucharest, Romania). Cervico-medistinal goiter – clinical and surgical assessment. Eur Respir J 2008; 32: Suppl. 52, 2141

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