Source: Annual Congress 2008 - Factors related to outcome of community-acquired pneumonia

Abstract

The aim of this study was to elucidate whether occupational exposure to gases, irritants or fumes increased the risk for pneumonia, especially lobar pneumonia.
Methods: The study population was a cohort of 52.511 occupationally exposed Swedish male construction workers and 41.063 unexposed male construction workers. Our definition of exposure to fumes (metal fumes and diesel exhaust), gases and irritants (organic solvents and reactive chemicals) was based on a job-exposure matrix with focus on exposure in the mid-1970s. The cohort was followed from 1971 to 2002, and the analysis of mortality due to pneumonia was adjusted for age, smoking and hypertension. Pneumonia was defined as 480-483, 485-486 and 487A according to the ICD9, and as J10-J16 and J18 according to the ICD10 classifications, respectively. Lobar pneumonia was defined as 481 (ICD 9) and J13 and J18.1 (ICD 10).
Results: Using the person-year method, stratifying for smoking, age and hypertension, exposure to fumes, gases and irritants was associated with an increased mortality from pneumonia (SRR=1.72, 95% CI 1.49-2.00, n=218). The risk for mortality due to lobar pneumonia was even more prominent (SRR=5.71, 95% CI 3.75-8.70, n=20).
Conclusion: Occupational exposure to gases and fumes among construction workers increases the risk for mortality due to pneumonia, in particular lobar pneumonia.

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Citations should be made in the following way:
I. Qvarfordt, K. Torén, I. Bergdahl, B. Järvholm (Göteborg, Umeå, Sweden). Exposure to gases and fumes increase the mortality from pneumonia. Eur Respir J 2008; 32: Suppl. 52, 1555

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