Respiratory virus and bacterial spectrum in healthy persons of organized closed collectives
T. S. Sologub, Y. V. Rezstova, N. V. Yakovleva, S. D. Zhogolev, N. V. Zueva, P. I. Ogarkov (St. Petersburg, Russian Federation)
Source: Annual Congress 2006 - Virus-induced respiratory tract infection
Session: Virus-induced respiratory tract infection
Session type: Oral Presentation
Number: 961
Disease area: Respiratory infections
Abstract Aim: to determine the spectrum and carriage rate of respiratory pathogens in healthy persons (HP) of closed collectives. Materials and methods: 317 healthy men (age 18-20) were twice examined during six months (interval 2-3 months) by virological and bacteriological methods. Results: respiratory viruses antigens were found in 11,7% of HP. The main of carriage infective agents were adenovirus (6,9%), M.pneumoniae (6,6%) and parainfluenzae virus (2,9%). However carriage rate of adenovirus was reduced 6-fold (1,1%) during observation. Associated agents were found in 10,8% of HP and the main composition was presented by adeno- and respiratory syncytial virus. The respiratory pathogenic bacteria were isolated in 38% of HP. S.pneumoniae was the leading agent (60%) of bacterial carriage and was stable revealed in 21,9% at double investigation. Penicillin resistance strains were detected in 15,3%. Carriage of H.influenzae was detected in 9,5%, Kl.pneumoniae – in 3,0%, S.aureus – in 14,9% but the last was decreased to 3,8% at 2-nd investigation. The later persons arrived, the more carriers were revealed. This fact may be explained by the ²mixing² factor due overcrowding and formation of ²infectious foci². Conclusion: it was established ²epidemiological constancy² of spectrum and carriage rate of respiratory pathogens in healthy persons of closed collectives. The almost total renovation of persons – carriers was revealed. Composition of respiratory pathogens in healthy persons is potencial etiological source for community acquired pneumoniae.
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T. S. Sologub, Y. V. Rezstova, N. V. Yakovleva, S. D. Zhogolev, N. V. Zueva, P. I. Ogarkov (St. Petersburg, Russian Federation). Respiratory virus and bacterial spectrum in healthy persons of organized closed collectives. Eur Respir J 2006; 28: Suppl. 50, 961
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