Source: Annual Congress 2006 - Clinical aspects of tuberculosis
Disease area: Paediatric lung diseases, Respiratory infections

Abstract

Patients diagnosed as miliary tuberculosis (MTb) in Dicle University Hospital were retrospectively investigated. There were 26 adult and 56 child cases during a 13 years period. There was a male predominance of the patients (32/24) in children and a female predominance (18/8) in adults. The mean age of the pediatric cases was 3.9±3.3 years and the adult cases was 35.1±15.5 years. Thirty eight (46.3%) patients had family history of tuberculosis. None of the patients had prior history of tuberculosis in the past. Dyspnea, chest pain, abdominal pain, fever and night sweating were more prominent among adults; while hepatomegaly, splenomegaly, convulsion, and diarrhea were more frequent among children. In the laboratory, hypoalbuminemia, elevated levels of liver transaminases and lactate dehydrogenase were more common among adults than in children. The diagnosis was proven microbiologically in overall 15 (18.3%) patients and consistent radiological findings were present in all patients. Among 56 pediatric cases there were 8 (14.3%) children with positive BCG scar and 16 (28.6%) children with positive reaction to 5TU tuberculin test. Twenty patients (24%), 14 children and 6 adults, had tuberculous meningitis accompanying the disease. We have found predisposing factors in 13 (15.9%) patients, 11 adults and 2 children. Overall 6 (7.3%) patients had died, of whom 2 had accompanying tuberculous meningitis, and 4 with predisposing factor. To get a good suspicion of early diagnosis and treatment, different characteristics of the adult and pediatric cases with MTb should be known.

Rating:

Share or cite this content

Citations should be made in the following way:
F. Gurkan, C. Tanrikulu, C. E. Dagli, A. Ece, A. Senyigit (Diyarbakir, Turkey). A comparative review of pediatric and adult cases with miliary tuberculosis. Eur Respir J 2006; 28: Suppl. 50, 821

Member's Comments

No comment yet.

Related content which might interest you: Miliary tuberculosis: a clinical review Source: Eur Respir J 2002; 20: Suppl. 38, 362s Year: 2002 Extrapulmonary tuberculosis: a retrospective analysis of 147 cases Source: Eur Respir J 2003; 22: Suppl. 45, 589s Year: 2003 A retrospective study of the presentation, diagnosis and outcomes of miliary tuberculosis at a UK centre Source: Annual Congress 2007 - Clinical tuberculosis Year: 2007 The diagnostic approaches and outcome of miliary tuberculosis: seven-years experience Source: Eur Respir J 2001; 18: Suppl. 33, 498s Year: 2001 Clinical and radiological aspects of patients with miliary tuberculosis Source: Annual Congress 2008 - Difficult tuberculosis cases Year: 2008 Miliary tuberculosis: A statistical study about 21 cases Source: Annual Congress 2010 - Special treatment options in tuberculosis Year: 2010 Retrospective study of abdominal tuberculosis without pulmonary involvement: a difficult to diagnose form of extrapulmonary tuberculosis Source: International Congress 2018 – Pulmonary tuberculosis: long term complications, rehabilitation and challenges Year: 2018 The evaluation of child cases with tuberculosis Source: Eur Respir J 2006; 28: Suppl. 50, 20s Year: 2006 Non tuberculous mycobacteria lung infection. Study of 31 cases and review of the literature Source: Eur Respir J 2004; 24: Suppl. 48, 644s Year: 2004 Late-breaking abstract: A case of miliary TB presenting with large pneumothorax Source: Annual Congress 2011 - Clinical challenges in tuberculosis Year: 2011 The retrospective evaluation of pulmonary tuberculosis cases with DM Source: Eur Respir J 2004; 24: Suppl. 48, 421s Year: 2004 Non-tuberculous mycobacterium infection in adult patients: a 10-year single-centre experience Source: International Congress 2019 – Clinical investigations of non-TB mycobacterial infection Year: 2019 Retrospective analysis of 351 extrapulmonary tuberculosis cases diagnosed in a tertiary multidisciplinary hospital Source: Annual Congress 2008 - Problems in managing pulmonary and extrapulmonary tuberculosis Year: 2008 Tuberculous spondylitis: the clinical features, diagnosis and treatment of twenty six patients with spinal tuberculosis and a review of the literature Source: Eur Respir J 2005; 26: Suppl. 49, 419s Year: 2005 Long-term follow-up study of patients with pneumoconiosis complicated by nontuberculous mycobacterial lung disease: report of four cases Source: Eur Respir J 2001; 18: Suppl. 33, 443s Year: 2001 Pulmonary tuberculosis in immunocompromized women: a comparative study Source: Annual Congress 2007 - Epidemiology of tuberculosis Year: 2007 A review of the diagnosis and treatment of smear-negative pulmonary tuberculosis Source: Annual Congress 2008 - Problems in managing pulmonary and extrapulmonary tuberculosis Year: 2008 Extrapulmonary tuberculosis: clinical and epidemiological spectrum of 636 cases Source: Eur Respir J 2003; 22: Suppl. 45, 588s Year: 2003 The aging and extrapulmonary tuberculosis: a 90-year-old case with testicular tuberculosis Source: Annual Congress 2007 - Tuberculosis Year: 2007 Mycobacterium tuberculosis transmission from patients with drug-resistant compared to drug-susceptible TB: a systematic review and meta-analysis Source: Eur Respir J, 50 (4) 1701044; 10.1183/13993003.01044-2017 Year: 2017