Minimum inhibitory concentrations and sequencing data have to be analysed in more detail to set provisional epidemiological cut-off values for Mycobacterium tuberculosis complex
Claudio U. Köser, Florian P. Maurer
Source: Eur Respir J, 61 (5) 2202397; 10.1183/13993003.02397-2022
  
Abstract
There is a clear need for a high-quality broth microdilution (BMD) assay for quantitative antimicrobial susceptibility testing (AST) for the Mycobacterium tuberculosis complex (MTBC) [1]. The BMD plate developed by the CRyPTIC Consortium, therefore, represents an important advance [2]. However, the analysis of the resulting data has several limitations.
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Claudio U. Köser, Florian P. Maurer. Minimum inhibitory concentrations and sequencing data have to be analysed in more detail to set provisional epidemiological cut-off values for Mycobacterium tuberculosis complex. Eur Respir J, 61 (5) 2202397; 10.1183/13993003.02397-2022
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