Anemia severely reduces health-related quality of life in COPD patients Receiving long-term home non-invasive ventilation

M. Wollsching-Strobel (Cologne, Germany), S. Schwarz (Cologne, Germany), T. Mathes (Cologne, Germany), D. Majorski (Cologne, Germany), P. Heidari (Cologne, Germany), D. Kroppen (Cologne, Germany), F. Magnet (Cologne, Germany), W. Windisch (Cologne, Germany)

Source: Respiratory Failure and Mechanical Ventilation Conference 2022 - Opening session: Essentials of respiratory physiology - Assessment of respiratory muscle function - Pulmonary infections in mechanically ventilated patients - Telemonitoring of patients with chronic respiratory failure - Diagnostics and interventions - Acute respiratory failure: COVID-19 - Interstitial lung disease and pulmonary hypertension - Early rehabilitation - Acute respiratory failure: Invasive mechanical ventilation - HFNO and NIV for acute hypoxemic failure - Longterm NIV miscellaneous - Controversies in acute respiratory failure - The role of respiratory muscle dysfunction in weaning failure - Transitions in chronic NIV - New insights in weaning from invasive ventilation - Noninvasive ventilation (NIV) in the clinical practice: How do I do it? - Difficult weaning from mechanical ventilation - Chronic ventilatory support in different diseases: Is one way fitting all? - Strategies to optimise early mobilisation and rehabilitation in intensive care - Noninvasive ventilation (NIV) in the clinical practice: How do I do it? - Acute respiratory failure: Hypercapnic and diagnosis - Weaning from mechanical ventilation - Mechanical ventilation in the acute setting - Health-related quality of life in mechanical ventilation - Long-term noninvasive ventilation: Diagnosis and outcome

Session: Long-term noninvasive ventilation: Diagnosis and outcome
Session type: Oral poster discussion
Number: 124

Abstract

Aims: To assess the influence of anemia on health-related quality of life (HRQL) in COPD patients receiving long-term non-invasive ventilation (NIV).

Methods: In this prospective single-center cohort study, COPD patients on long-term NIV were analyzed between June 2015-May 2020. Linear multiple regression analyses were performed using the Severe Respiratory Insufficiency Questionnaire (SRI) along with the following variables: sex, age, body mass index, duration of NIV, exacerbation history (=1 vs >1 in the previous year), the updated Charlson comorbidity index, hemoglobin levels and anemia (WHO criteria).

Results: Anemia was identified in 32.8% (N=128). Anemia (mean difference-8.4,95%CI-2.0/-14.9 SRI points,P=0.011) and exacerbations (mean difference-9.9,95%CI-4.3/-15.5 SRI points,P=0.001) each had a negative impact on SRI summary scores. Exacerbations were negatively associated with 6/7 SRI subscale scores, while anemia was negatively associated with 4/7. SRI summary scores dropped by 1.5 points for every g/dl of hemoglobin (P=0.08). No other variables had an influence on the SRI scores.

Conclusion: The present study has shown that within a cohort of COPD patients undergoing long-term NIV, one-third were identified as anemic. Furthermore, anemia, like exacerbation history, was found to have a considerable negative impact on HRQL that is specific to patients with chronic respiratory failure.

Rating:

You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Wollsching-Strobel (Cologne, Germany), S. Schwarz (Cologne, Germany), T. Mathes (Cologne, Germany), D. Majorski (Cologne, Germany), P. Heidari (Cologne, Germany), D. Kroppen (Cologne, Germany), F. Magnet (Cologne, Germany), W. Windisch (Cologne, Germany). Anemia severely reduces health-related quality of life in COPD patients Receiving long-term home non-invasive ventilation. Respiratory Failure and Mechanical Ventilation Conference 2022 - Opening session: Essentials of respiratory physiology - Assessment of respiratory muscle function - Pulmonary infections in mechanically ventilated patients - Telemonitoring of patients with chronic respiratory failure - Diagnostics and interventions - Acute respiratory failure: COVID-19 - Interstitial lung disease and pulmonary hypertension - Early rehabilitation - Acute respiratory failure: Invasive mechanical ventilation - HFNO and NIV for acute hypoxemic failure - Longterm NIV miscellaneous - Controversies in acute respiratory failure - The role of respiratory muscle dysfunction in weaning failure - Transitions in chronic NIV - New insights in weaning from invasive ventilation - Noninvasive ventilation (NIV) in the clinical practice: How do I do it? - Difficult weaning from mechanical ventilation - Chronic ventilatory support in different diseases: Is one way fitting all? - Strategies to optimise early mobilisation and rehabilitation in intensive care - Noninvasive ventilation (NIV) in the clinical practice: How do I do it? - Acute respiratory failure: Hypercapnic and diagnosis - Weaning from mechanical ventilation - Mechanical ventilation in the acute setting - Health-related quality of life in mechanical ventilation - Long-term noninvasive ventilation: Diagnosis and outcome

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.

You must Login to comment this presentation.