Losartan reduces cigarette smoke-induced airway inflammation and mucus hypersecretion

Michael D. Kim, Nathalie Baumlin, John S. Dennis, Makoto Yoshida, Adrian Kis, Carolina Aguiar, Andreas Schmid, Eliana Mendes, Matthias Salathe

Source: ERJ Open Res, 7 (1) 00394-2020; 10.1183/23120541.00394-2020
Journal Issue: January
Disease area: Airway diseases

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Michael D. Kim, Nathalie Baumlin, John S. Dennis, Makoto Yoshida, Adrian Kis, Carolina Aguiar, Andreas Schmid, Eliana Mendes, Matthias Salathe. Losartan reduces cigarette smoke-induced airway inflammation and mucus hypersecretion. ERJ Open Res, 7 (1) 00394-2020; 10.1183/23120541.00394-2020

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Tiotropium inhalation prevents acute cigarette smoke-induced airway inflammation in mice
Source: Annual Congress 2009 - Airway inflammation and host defence
Year: 2009

Ceramide-1-phosphate inhibits cigarette smoke-induced airway inflammation
Source: Eur Respir J 2015; 45: 1669-1680
Year: 2015



LPS accelerates cigarette smoke-induced deterioration in respiratory function and airway inflammation in mice
Source: Annual Congress 2007 - New treatments for asthma and COPD - experimental evidence
Year: 2007


Role of activin-A in cigarette smoke-induced inflammation and COPD
Source: Eur Respir J 2014; 43: 1028-1041
Year: 2014



Effects of N-acetylcysteine on airway inflammation, airway hyperresponsiveness and abnormal lung function in chronic ozone-induced COPD model
Source: Annual Congress 2012 - Animal models of asthma and COPD and late-breaking abstracts on RCT in asthma and COPD
Year: 2012

Tobacco smoking alters the relationship between airway inflammation and airway hyperresponsiveness in asthma
Source: Annual Congress 2012 - Cell biology and inflammatory gene expression in chronic lung disease
Year: 2012

LSC Abstract – Cigarette smoke exposure accelerates airway mucus accumulation and inflammation in ENaC-overexpressed mice
Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects
Year: 2015

Resistive breathing aggravates cigarette smoke-induced pulmonary inflammation.
Source: International Congress 2017 – Smoking and molecular findings
Year: 2017




Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy
Source: Eur Respir J 2014; 43: 1211-1212
Year: 2014


Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy
Source: Eur Respir J 2014; 43: 1208-1211
Year: 2014


Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy
Source: Eur Respir J 2013; 42: 350-361
Year: 2013



Cigarette smoking inhibits LTA4H aminopeptidase activity and contributes to chronic neutrophilic airway inflammation and COPD
Source: Annual Congress 2011 - COPD: clinical studies and animal cell models
Year: 2011


Osteopontin exacerbates airway hyperresponsiveness and lung remodeling in chronic asthma
Source: Annual Congress 2008 - Basic science in asthma and COPD
Year: 2008

Effects of active and passive smoking on allergic airway inflammation and airway hyperresponsiveness in mice
Source: Eur Respir J 2002; 20: Suppl. 38, 310s
Year: 2002

Effect of sildenafil on mucus hypersecretion of rat airway
Source: Eur Respir J 2007; 30: Suppl. 51, 523s
Year: 2007

Smoking cessation improves both direct and indirect airway hyperresponsiveness in COPD
Source: Eur Respir J 2004; 24: 391-396
Year: 2004



Cigarette smoke-induced airway neurogenic inflammation is mediated by α,ß-unsaturated aldehydes and the TRPA1 receptor.
Source: Annual Congress 2008 - Recent advances in the pathogenesis and treatment of asthma and COPD
Year: 2008



Pioglitazone inhibits obesity-related airway hyperreactivity
Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms
Year: 2020


Inhaled insulin does not trigger lung inflammation and airway remodelling
Source: Eur Respir J 2009; 33: 444-445
Year: 2009