COPD sputum eosinophils: relationship to blood eosinophils and the effect of inhaled PDE4 inhibition
Dave Singh, Henrik Watz, Kai Michael Beeh, Oliver Kornmann, Brian Leaker, Brendan Colgan, Germano Lucci, Aida Emirova, Marie Anna Nandeuil, Debora Santoro, Deborah Balzano, Mirco Govoni
Source: Eur Respir J, 56 (2) 2000237; 10.1183/13993003.00237-2020
Disease area: Airway diseases
Rating:
You must login to grade this presentation.
Share or cite this content
Citations should be made in the following way:
Dave Singh, Henrik Watz, Kai Michael Beeh, Oliver Kornmann, Brian Leaker, Brendan Colgan, Germano Lucci, Aida Emirova, Marie Anna Nandeuil, Debora Santoro, Deborah Balzano, Mirco Govoni. COPD sputum eosinophils: relationship to blood eosinophils and the effect of inhaled PDE4 inhibition. Eur Respir J, 56 (2) 2000237; 10.1183/13993003.00237-2020
You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.
Member's Comments
Related content which might interest you:
Related content which might interest you:
Dissosiation between eosinophils in sputum and blood of asthmatics Source: Eur Respir J 2002; 20: Suppl. 38, 309s Year: 2002
Effect of salmeterol in asthmatic patients with low sputum eosinophils Source: Eur Respir J 2001; 18: Suppl. 33, 336s Year: 2001
Regular salbutamol use increases CXCL8 responses in asthma: relationship to the eosinophil response Source: Eur Respir J 2003; 22: 118-126 Year: 2003
Blood eosinophils in COPD: relationship with CLCA1 and mucus production Source: International Congress 2018 – Studies on the mechanisms underlying airway disease Year: 2018
Sputum eosinophil counts in a large population of mild-to-moderate asthmatics: distribution, relationship with methacholine bronchial responsiveness and influence of a regular treatment with low doses of inhaled corticosteroids Source: Eur Respir J 2001; 18: Suppl. 33, 531s Year: 2001
Possible anti-inflammatory effect of salmeterol against interleukin-8 and neutrophil activation in asthma in vivo Source: Eur Respir J 2003; 21: 994-999 Year: 2003
Mechanisms of noneosinophilic asthma Source: Annual Congress 2007 - Inflammatory phenotypes in airway disease Year: 2007
Increasing sputum basophils is a marker for eosinophil-dominant airway inflammation in adult asthma Source: International Congress 2018 – Airway disease: recent discoveries Year: 2018
A study on the relevance of eosinophil counts in induced sputum and FENO and lung functions in asthmatics Source: Annual Congress 2010 - Induced sputum in relation: a fresh look on phenotyping and monitoring Year: 2010
Blood eosinophils do not reliably reflect airway eosinophils in asthmatic children Source: International Congress 2018 – Studying novel biomarkers in asthma and COPD Year: 2018
Cysteinyl-leukotrienes contribute to sputum eosinophil chemotactic activity in asthma Source: Eur Respir J 2005; 26: Suppl. 49, 734s Year: 2005
Blood eosinophils as a marker of response to inhaled corticosteroids in COPD Source: Eur Respir J 2016; 47:1374-1382 Year: 2016
Eosinophils in peripheral blood are associated with eosinophils in sputum, BAL, and bronchial biopsies in COPD Source: Eur Respir J 2004; 24: Suppl. 48, 306s Year: 2004
Correlation between sputum and blood eosinophils in asthmatic and COPD patients with comorbidities. Source: International Congress 2018 – Airway disease: recent discoveries Year: 2018
Sputum analysis reveals eosinophilic inflammation in difficult-to-control asthma patients with low blood eosinophils and FENO. Source: Virtual Congress 2020 – Monoclonal antibodies; randomised controlled trials and real-world studies in asthma Year: 2020
Blood eosinophils do not reflect lung tissue eosinophils in COPD Source: International Congress 2017 – Systemic and airway biomarkers Year: 2017
Sputum eosinophilia vs exhaled NO as markers of airways inflammation in asthma: relationship with asthma control Source: Eur Respir J 2005; 26: Suppl. 49, 736s Year: 2005
Absence of sputum eosinophils in subjects with symptomatic asthma on inhaled budesonide Source: Eur Respir J 2002; 20: Suppl. 38, 274s Year: 2002
The eosinophil is important in asthma after all – Con Source: Annual Congress 2006 - Pro/Con: asthma is (not) an inflammatory disease Year: 2006
Monitoring of sputum eosinophils in long-term treatment of bronchial asthma Source: Eur Respir J 2002; 20: Suppl. 38, 111s Year: 2002