Source: Annual Congress 2007 - Epidemiology of tuberculosis II
Disease area: Respiratory infections, Thoracic oncology

Abstract

The diagnosis of tuberculosis(TB) is mainly based on the presence of acid-fast bacilli. In absence of the bacilli, its confirmation may be required via more invasive methods. The study included the TB cases had during last 5 years. The contribution of bronchoscopy in the diagnosis and bronchoscopic findings were evaluated. Bronchoscopic lavage(BL) and post bronchoscopic sputum(PBS) were taken in all cases. A biopsy from lesion and transbronchial biopsy were performed in cases with endobronchial lesion and military pattern on chest X-ray. Of 177 cases with smear negative,96(54.2%) were undergone diagnostic bronchoscopy. Of them,73(76%) were diagnosed as TB, pathologic diagnosis in 23 cases and AFB positivity on smear of BL or PBS in 45 cases, via bronchoscopy. In the cases diagnosed with bronchoscopy, the duration of symptoms was lower and a serum level of CRP was higher than that of undiagnosed. However, the difference was no significant. In the cases undergone bronchoscopy endobronchial lesion(TB) was determined in 17 cases(17,7%). Of the cases, 7 had exudative lesions,4 had cavitary lesion,5 had mediastinal lymphadenomegaly and 1 had no lesion on chest X-ray. In the cases with endobronchial lesion duration of symptoms and diameter of PPD was lower and serum level of CRP was higher than those had no endobronchial lesion. However, the difference was no significant. As a conclusion, bronchoscopy provides a substantial contribution to the diagnosis of smear negative cases. The results suggest that it is very likely to determine endobronchial lesion and to increase diagnostic accuracy in the cases with shorter symptom duration and increases serum CRP levels.

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Citations should be made in the following way:
F. F. Aghayev, F. A. Mammadyarova (Baku, Azerbaijan). Endobronchial tuberculosis and the value of bronchoscopy in the diagnosis of cases with smear negative tuberculosis. Eur Respir J 2007; 30: Suppl. 51, 3821

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