Severe asthma outcomes over 18-months treatment with mepolizumab, and comorbidities in non-responders.

L. Elsey (Manchester, United Kingdom), J. Wingfield-Derby (Manchester, United Kingdom), L. Holmes (Manchester, United Kingdom), L. Maguire (Manchester, United Kingdom), K. Newman (Manchester, United Kingdom), T. Pantin (Manchester, United Kingdom), S. Fowler (Manchester, United Kingdom)

Source: Virtual Congress 2020 – Monoclonal antibodies; randomised controlled trials and real-world studies in asthma
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
L. Elsey (Manchester, United Kingdom), J. Wingfield-Derby (Manchester, United Kingdom), L. Holmes (Manchester, United Kingdom), L. Maguire (Manchester, United Kingdom), K. Newman (Manchester, United Kingdom), T. Pantin (Manchester, United Kingdom), S. Fowler (Manchester, United Kingdom). Severe asthma outcomes over 18-months treatment with mepolizumab, and comorbidities in non-responders.. 2256

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Severe asthma outcomes over two years of therapy with mepolizumab
Source: Virtual Congress 2021 – Advances in asthma treatment: monoclonal antibodies
Year: 2021


Outcomes over the first two years of treatment with mepolizumab in severe asthma
Source: Eur Respir J, 58 (6) 2101313; 10.1183/13993003.01313-2021
Year: 2021



Adherence to corticosteroids and clinical outcomes in mepolizumab therapy for severe asthma
Source: Eur Respir J, 55 (5) 1902259; 10.1183/13993003.02259-2019
Year: 2020



A longitudinal follow-up of severe asthma patients receiving reslizumab
Source: International Congress 2017 – Asthma management
Year: 2017


Early treatment response may predict long-term mepolizumab benefit in severe asthma
Source: International Congress 2019 – Treatment of asthma with monoclonal antibodies
Year: 2019


Stopping versus continuing long-term mepolizumab treatment in severe eosinophilic asthma (COMET study)
Source: Eur Respir J, 59 (1) 2100396; 10.1183/13993003.00396-2021
Year: 2022



Add-on omalizumab therapy reduces clinically significant and severe asthma exacerbations, and improves FEV1 in patients with severe persistent allergic asthma irrespective of age
Source: Eur Respir J 2005; 26: Suppl. 49, 48s
Year: 2005

The characteristics of treatment failure with omalizumab in patients with severe asthma: The impact of eosinophilic complication
Source: Virtual Congress 2020 – Monoclonal antibodies in asthma
Year: 2020

Severe outcomes of COVID-19 among patients with COPD and asthma
Source: ERJ Open Res, 7 (1) 00594-2020; 10.1183/23120541.00594-2020
Year: 2021



Patient-reported versus objective adherence and exacerbation rates in severe asthma.
Source: Virtual Congress 2020 – Clinical parameters in severe asthma
Year: 2020


Inflammatory biomarkers in the evaluation of two-year  outcomes  of omalizumab treatment in severe allergic asthma.
Source: International Congress 2018 – Biomarkers for evaluating asthma
Year: 2018

Effect of omalizumab on the risk of hospitalisation in patients with uncontrolled severe asthma in real-life. The PAX-LASER cohort
Source: Annual Congress 2010 - Aspects of severe asthma
Year: 2010


Predictors of response to therapy with omalizumab in patients with severe allergic asthma–a real life study
Source: International Congress 2017 – Monitoring asthma control
Year: 2017


Evaluation of therapeutic response to anti-IL5 treatment in severe eosinophilic asthma patients no responders to omalizumab
Source: International Congress 2019 – Treatment of asthma with monoclonal antibodies
Year: 2019


Does adherence to ICS/LABA therapy affect response to mepolizumab in the treatment of severe asthma?
Source: International Congress 2019 – Real-world experience of monoclonal antibodies in asthma
Year: 2019

The 1-year cost-effectiveness of roflumilast for the treatment of severe to very severe COPD patients
Source: Eur Respir J 2007; 30: Suppl. 51, 194s
Year: 2007

Severe asthma and biologic therapies during COVID-19: supporting patients care with home administration of mepolizumab and omalizumab
Source: Virtual Congress 2021 – Asthma clinical trials and real-life studies
Year: 2021


Exacerbations of severe asthma in patients treated with mepolizumab
Source: Eur Respir J, 52 (6) 1801127; 10.1183/13993003.01127-2018
Year: 2018



Symptom pattern and treatment for people non-compliant with asthma medication
Source: Annual Congress 2005 - Allergic rhinitis and asthma in primary care
Year: 2005


Continued long-term mepolizumab in severe eosinophilic asthma protects from asthma worsening versus stopping mepolizumab: COMET trial
Source: Virtual Congress 2020 – Recent innovations regarding the mechanisms and treatments of asthma
Year: 2020