Arsenic trioxyde inhibits the functions on lung fibroblasts derived from patients with idiopathic pulmonary fibrosis

A. Joannes (RENNES, France), C. Morzadec (RENNES, France), M. Duclos (RENNES, France), N. Bellamri (RENNES, France), F. Llamas Gutierrez (RENNES, France), B. Richard De Latour (RENNES, France), S. Wollin (Biberach an der Riss, Germany), S. Jouneau (RENNES, France), L. Vernhet (RENNES, France)

Source: International Congress 2019 – Translational aspects of idiopathic pulmonary fibrosis
Session: Translational aspects of idiopathic pulmonary fibrosis
Session type: Poster Discussion
Number: 5373
Disease area: Interstitial lung diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
A. Joannes (RENNES, France), C. Morzadec (RENNES, France), M. Duclos (RENNES, France), N. Bellamri (RENNES, France), F. Llamas Gutierrez (RENNES, France), B. Richard De Latour (RENNES, France), S. Wollin (Biberach an der Riss, Germany), S. Jouneau (RENNES, France), L. Vernhet (RENNES, France). Arsenic trioxyde inhibits the functions on lung fibroblasts derived from patients with idiopathic pulmonary fibrosis. 5373

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Antifibrosic effects of sulforaphane in human lung fibroblasts from idiopathic pulmonary fibrosis
Source: Annual Congress 2011 - New insights in the treatment of idiopathic pulmonary fibrosis
Year: 2011

Anti-fibrotic effects of pirfenidone in lung fibroblasts derived from patients with idiopathic pulmonary fibrosis
Source: International Congress 2015 – IPF: from bench to bedside
Year: 2015

Effect of nintedanib on hyaluronic acid metabolism in lung fibroblasts derived from patients with idiopathic pulmonary fibrosis
Source: International Congress 2015 – IPF: from bench to bedside
Year: 2015

Effect of pirfenidone on TGF-beta-induced pro-fibrotic effects in primary human lung cells derived from patients with idiopathic pulmonary fibrosis
Source: International Congress 2014 – ILDs 2
Year: 2014

Effect of nintedanib, pirfenidone, N-acetylcysteine and their combinations on cultured myofibroblast-type cells derived from patients with asbestosis and idiopathic pulmonary fibrosis
Source: International Congress 2015 – Airway remodelling: recent developments
Year: 2015

Expression of redox-related selenoprotein P in lung tissues and fibroblasts obtained from the patients with idiopathic pulmonary fibrosis
Source: Eur Respir J 2006; 28: Suppl. 50, 825s
Year: 2006

Nintedanib (BIBF 1120) prevents TGF-beta-induced pro-fibrotic effects in primary human lung myofibroblasts derived from patients with idiopathic pulmonary fibrosis
Source: International Congress 2014 – ILDs 1
Year: 2014

Treprostinil effectively inhibits PDGF and TGF-ß1 induced extracellular matrix composition by IPF fibroblasts
Source: International Congress 2015 – Therapeutic approaches in inflammatory lung disease
Year: 2015

Increased polysialylation in lung tissue of patients with idiopathic pulmonary fibrosis
Source: Annual Congress 2011 - Cell biology of lung disease
Year: 2011


DPP-4 is overexpressed in lung tissue from idiopathic pulmonary patients and activates lung fibroblasts
Source: Virtual Congress 2020 – Translational aspects of idiopathic pulmonary fibrosis
Year: 2020

NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFβ1-induced fibroblast differentiation into myofibroblasts
Source: Annual Congress 2009 - From emphysema to fibrosis: mechanisms of cellular remodelling in the diseased lung
Year: 2009

Loss of PTEN induced lung fibroblasts exhibiting similar pathogenic features to cancer cells in idiopathic pulmonary fibrosis
Source: International Congress 2014 – ILDs 2
Year: 2014


Upregulation of Fas-signalling molecules in lung epithelial cells from patients with idiopathic pulmonary fibrosis
Source: Eur Respir J 2001; 17: 180-189
Year: 2001



Distinct gene expression profiles of cultured stromal cells from the patients with idiopathic pulmonary fibrosis and lung adenocarcinoma
Source: International Congress 2015 – Translational studies in airway cell biology
Year: 2015

Nintedanib prevents IL-1beta-stimulated proliferation of primary human lung fibroblasts from patients with idiopathic pulmonary fibrosis or from control donors
Source: International Congress 2014 – ILDs: pathogenesis and clinical features
Year: 2014

Role of Bcl-xL in hepatocyte growth factor elicited epithelial protection in idiopathic lung fibrosis
Source: Annual Congress 2013 –Idiopathic pulmonary fibrosis: pathogenesis
Year: 2013

Apoptosis in epithelial cells in patients with idiopathic pulmonary fibrosis
Source: Eur Respir J 2004; 24: Suppl. 48, 481s
Year: 2004

Does apoptosis evasion only affect fibroblasts from idiopathic pulmonary fibrosis?
Source: Annual Congress 2013 –Cell signalling and inflammation: what's new in 2013?
Year: 2013

Reactivation of developmental pathways in idiopathic pulmonary fibrosis: FGF9 and FGF18 modulate the phenotype of control and fibrotic human lung fibroblasts in vitro
Source: International Congress 2015 – IPF: from bench to bedside
Year: 2015

Decreased BCL-2 expression in alveolar macrophages of patients with idiopathic pulmonary fibrosis
Source: Annual Congress 2010 - Biomarkers in diffuse parenchymal lung disease
Year: 2010