Hyperhomocysteinemia promotes pulmonary emphysema in murine model of COPD

H. Nakano (Yamagata, Japan), S. Inoue (Yamagata, Japan), H. Machida (Yamagata, Japan), K. Sato (Yamagata, Japan), M. Sato (Yamagata, Japan), Y. Tokairin (Yamagata, Japan), A. Igarashi (Yamagata, Japan), M. Watanabe (Yamagata, Japan), Y. Shibata (Fukushima, Japan)

Source: International Congress 2019 – Involvement of the environment and inflammation in pulmonary remodelling
Session: Involvement of the environment and inflammation in pulmonary remodelling
Session type: Thematic Poster
Number: 2448
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
H. Nakano (Yamagata, Japan), S. Inoue (Yamagata, Japan), H. Machida (Yamagata, Japan), K. Sato (Yamagata, Japan), M. Sato (Yamagata, Japan), Y. Tokairin (Yamagata, Japan), A. Igarashi (Yamagata, Japan), M. Watanabe (Yamagata, Japan), Y. Shibata (Fukushima, Japan). Hyperhomocysteinemia promotes pulmonary emphysema in murine model of COPD. 2448

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
IL-23 is essential to the development of elastase-induced pulmonary inflammation and emphysema
Source: International Congress 2016 – New findings in mucosal immunology
Year: 2016

Desmosin as a marker for tissue injury in COPD
Source: Annual Congress 2007 - α1-Antitrypsin deficiency: molecular and clinical news
Year: 2007


Cigarette smoke induced pulmonary emphysema is attenuated in CCR6 deficient mice
Source: Annual Congress 2006 - Cell biology of asthma and COPD
Year: 2006


Caspase inhibition reduces severe pulmonary hypertension in the AdTGF-1β/SU5416 model of angioproliferative pulmonary hypertension and lung fibrosis
Source: Annual Congress 2011 - Experimental pulmonary hypertension
Year: 2011

Suppressed pulmonary expression of leptin in lipopolysaccharide-induced acute and chronic lung inflammation
Source: Annual Congress 2006 - Novel pathogenic aspects of acute lung injury and acute respiratory distress syndrome (ARDS)
Year: 2006


Sirtuin3 reduces acute lung inflammation and emphysematous aggravation in COPD exacerbation mouse model
Source: International Congress 2019 – New molecular signatures in COPD, lung cancer and a1-antitrypsin deficiency
Year: 2019


Acute exacerbations and pulmonary hypertension in advanced idiopathic pulmonary fibrosis
Source: Eur Respir J 2012; 40: 93-100
Year: 2012



A novel chronic murine model of idiopathic pulmonary fibrosis
Source: International Congress 2018 – Pulmonary fibrosis: from models to patients
Year: 2018


Pulmonary function measures predict mortality differently in IPF versus combined pulmonary fibrosis and emphysema
Source: Eur Respir J 2011; 37: 176-183
Year: 2011



Alveolar remodelling in COPD
Source: Annual Congress 2006 - PG15 - Remodelling and repair in lung disease
Year: 2006


Pulmonary vascular involvement in chronic obstructive pulmonary disease
Source: Eur Respir J 2003; 22: 28S-32S
Year: 2003



Evidence of renal and pulmonary endothelial dysfunction in chronic obstructive pulmonary disease (COPD)
Source: International Congress 2016 – New signalling pathways in COPD
Year: 2016

Pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema syndrome
Source: Eur Respir J 2010; 35: 105-111
Year: 2010



Increased rho-kinase activity is related to pulmonary endothelial dysfunction in patients with chronic obstructive pulmonary disease (COPD)
Source: Annual Congress 2008 - Pulmonary vascular biology
Year: 2008


The novel compound Sul-121 inhibits inflammation in experimental models of chronic obstructive pulmonary disease
Source: International Congress 2016 – New signalling pathways in COPD
Year: 2016

Systemic and pulmonary inflammation in chronic obstructive pulmonary disease (COPD)
Source: Annual Congress 2008 - Pathophysiology of COPD
Year: 2008


Systemic vascular function in chronic obstructive pulmonary disease
Source: Annual Congress 2013 –Pulmonary circulation: clinical diagnosis, imaging, biomarkers and treatment
Year: 2013

Endothelial progenitor cells and pulmonary vascular remodeling in chronic obstructive pulmonary disease (COPD)
Source: Eur Respir J 2004; 24: Suppl. 48, 435s
Year: 2004

The impact of emphysema in pulmonary fibrosis
Source: Eur Respir Rev 2013; 22: 153-157
Year: 2013



Peripheral lung remodelling in asthma and chronic obstructive pulmonary disease
Source: Eur Respir J 2004; 24: 893-894
Year: 2004