Cigarette smoke and diesel particles repress functional responses in lung epithelial progenitors

X. Wu (Groningen, Netherlands), S. Bos (Groningen, Netherlands), M. Schmidt (Groningen, Netherlands), L. Kistemaker (Groningen, Netherlands), R. Gosens (Groningen, Netherlands)

Source: International Congress 2019 – Involvement of the environment and inflammation in pulmonary remodelling
Session: Involvement of the environment and inflammation in pulmonary remodelling
Session type: Thematic Poster
Number: 2437
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
X. Wu (Groningen, Netherlands), S. Bos (Groningen, Netherlands), M. Schmidt (Groningen, Netherlands), L. Kistemaker (Groningen, Netherlands), R. Gosens (Groningen, Netherlands). Cigarette smoke and diesel particles repress functional responses in lung epithelial progenitors. 2437

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Cigarette smoke extract and diesel particles result in the production of pro-inflammatory molecules from human primary lung fibroblast strains and pulmonary epithelial cells
Source: Eur Respir J 2001; 18: Suppl. 33, 413s
Year: 2001

Early transcriptional responses of bronchial epithelial cells following exposure to whole cigarette smoke
Source: Virtual Congress 2021 – Early manifestations of chronic respiratory disease: zooming in at the epithelial barrier
Year: 2021



Impact of PM2.5 on cigarette smoke exposed airway epithelial cells and lung tissues
Source: International Congress 2017 – Cigarette smoke and particulate matter: basic science and clinical aspects
Year: 2017

Cigarette smoke induces a distinct fibrotic signature in bronchial epithelial cells
Source: Annual Congress 2012 - The smoking gun in COPD biology
Year: 2012

Z-Alpha-1-antitrypsin and cigarette smoke extract impair apoptosis in human bronchial epithelial cells
Source: Eur Respir J 2006; 28: Suppl. 50, 797s
Year: 2006

Exposure to cigarette smoke affects the response of dendritic cells to pneumococcus
Source: Annual Congress 2011 - Phagocytes and dendritic cells
Year: 2011

Effect of cigarette smoke on proteasome function in alveolar epithelial cells
Source: Annual Congress 2011 - Epithelial cell biology
Year: 2011

Cigarette smoke down-regulates the expression of β-catenin in primary human lung fibroblasts
Source: Annual Congress 2011 - Lung cell biology
Year: 2011

Comparisons on mitochondrial function following exposure of cigarette smoke extract and fine particulate matter in human bronchial epithelial cells
Source: International Congress 2019 – Involvement of the environment and inflammation in pulmonary remodelling
Year: 2019

Cigarette smoke exposure disrupts the molecular regulation of mitochondrial metabolism in human bronchial and alveolar epithelial cells
Source: ERS Lung Science Conference 2020
Year: 2020

Cigarette smoke extract induces barrier changes and senescence in primary bronchial epithelial cells
Source: International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms
Year: 2019

Cigarette smoke and TGF-β1 increase p21waf1/cip1 expression in alveolar epithelial cells
Source: Eur Respir J 2002; 20: Suppl. 38, 97s
Year: 2002

Murine lung airway fibroblasts drive fibrosis through STAT4 signaling after cigarette smoke exposure
Source: Annual Congress 2012 - The smoking gun in COPD biology
Year: 2012

Cigarette smoke exposure decreases CFLAR expression in bronchial epithelium, augmenting susceptibility for cell death and DAMP release
Source: International Congress 2018 – Regenerative and anti-fibrotic approaches
Year: 2018



Impairment of lung organoid formation by cigarette smoke treatment of mesenchymal cells
Source: International Congress 2018 – COPD: novel pathological mechanisms in the airway epithelium
Year: 2018


Cigarette smoke irreversibly binds to glutathione in airway epithelial cells
Source: Annual Congress 2007 - Molecular pathogenesis: focus on COPD and asthma
Year: 2007


A protective effect of FAM13A in human bronchial epithelial cells upon exposure to cigarette smoke
Source: International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms
Year: 2019

miRNA expression in the lung in response to cigarette smoke
Source: Annual Congress 2009 - miRNAs in inflammation and disease
Year: 2009


Effects of cigarette smoke extract on in vitro differentiated bronchial epithelial cells from subjects with and without COPD
Source: Eur Respir J 2006; 28: Suppl. 50, 854s
Year: 2006

Temporal effects of cigarette smoke associated to diesel exhaust particles in mice
Source: Annual Congress 2011 - Smoking-related diseases and smoking cessation
Year: 2011