The epigenetic modulator 5-aza-2’-deoxycytidine reduces the fibrotic response of human lung fibroblasts to TGFß1 in a novel, long term, 3D cell culture system.

M. Ward (Dublin, Ireland), D. Smart (Southampton, United Kingdom), J. Roberts (Southampton, United Kingdom), P. Monk (Southampton, United Kingdom), D. Davies (Southampton, United Kingdom), M. Jones (Southampton, United Kingdom), K. O'Reilly (Dublin, Ireland), J. Baugh (Dublin, Ireland)

Source: International Congress 2019 – New mechanistic insights into pulmonary fibrosis
Session: New mechanistic insights into pulmonary fibrosis
Session type: Thematic Poster
Number: 2430
Disease area: Interstitial lung diseases

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M. Ward (Dublin, Ireland), D. Smart (Southampton, United Kingdom), J. Roberts (Southampton, United Kingdom), P. Monk (Southampton, United Kingdom), D. Davies (Southampton, United Kingdom), M. Jones (Southampton, United Kingdom), K. O'Reilly (Dublin, Ireland), J. Baugh (Dublin, Ireland). The epigenetic modulator 5-aza-2’-deoxycytidine reduces the fibrotic response of human lung fibroblasts to TGFß1 in a novel, long term, 3D cell culture system.. 2430

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