e-learning
resources
Madrid 2019
Monday, 30.09.2019
Effects of environmental exposures in lung pathology and the underlying mechanisms
Login
Search all ERS
e-learning
resources
Disease Areas
Airways Diseases
Interstitial Lung Diseases
Respiratory Critical Care
Respiratory Infections
Paediatric Respiratory Diseases
Pulmonary Vascular Diseases
Sleep and Breathing Disorders
Thoracic Oncology
Events
International Congress
Courses
Webinars
Conferences
Research Seminars
Journal Clubs
Publications
Breathe
Monograph
ERJ
ERJ Open Research
ERR
European Lung White Book
Handbook Series
Guidelines
All ERS guidelines
e-learning
CME Online
Case reports
Short Videos
SpirXpert
Procedure Videos
CME tests
Reference Database of Respiratory Sounds
Radiology Image Challenge
Brief tobacco interventions
EU Projects
VALUE-Dx
ERN-LUNG
ECRAID
UNITE4TB
Disease Areas
Events
Publications
Guidelines
e-learning
EU Projects
Login
Search
Cigarette smoke extract inhibits the NLRP3 inflammasome in human macrophages and impairs cell metabolism via NLRP3-independent activation of Caspase-1
M. Buscetta (Palermo, Italy), S. Di Vincenzo (Palermo, Italy), E. Pace (Palermo, Italy), C. Cipollina (Palermo, Italy)
Source:
International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms
Session:
Effects of environmental exposures in lung pathology and the underlying mechanisms
Session type:
Thematic Poster
Number:
2409
Disease area:
Airway diseases
Rating:
You must
login
to grade this presentation.
Share or cite this content
Citations should be made in the following way:
M. Buscetta (Palermo, Italy), S. Di Vincenzo (Palermo, Italy), E. Pace (Palermo, Italy), C. Cipollina (Palermo, Italy). Cigarette smoke extract inhibits the NLRP3 inflammasome in human macrophages and impairs cell metabolism via NLRP3-independent activation of Caspase-1. 2409
You must
login
to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.
Member's Comments
No comment yet.
You must
Login
to comment this presentation.
Related content which might interest you:
Panel discussion on ERS Statement – A core outcome set for clinical trials evaluating the management of COPD exacerbations
ERS statement: a core outcome set for clinical trials evaluating the management of COPD exacerbations
Evidence-based eHealth for COPD
Related content which might interest you:
Cigarette smoke induces the release of CXCL-8 from human bronchial epithelial cells via TLRs and the induction of inflammasome
Source: Annual Congress 2011 - Epithelial cell biology
Year: 2011
Cigarette smoke suppresses mast cell maturation and cytokine release independent of TLR4 signaling
Source: Annual Congress 2012 - Basic and translational studies in COPD
Year: 2012
Andrographolide inhibits the activation of NLRP3 inflammasome in patients with COPD
Source: International Congress 2018 – Preclinical pharmacology: novel targets in airway inflammation, narrowing and neural control
Year: 2018
Caspase-1 activation by cigarette smoke occurs via TLR4/TRIF/caspase-8 axis leading to metabolic alterations in human macrophages
Source: ERS Lung Science Conference 2020
Year: 2020
Cigarette smoke prevents caspase activation and apoptosis and instead promotes necrosis
Source: Annual Congress 2003 - Cigarette smoke: how it does its dirty work
Year: 2003
Late Breaking Abstract - 17-oxo-DHA inhibits the NLRP3 inflammasome downstream of mitochondrial ROS and ERK pathway
Source: International Congress 2017 – New Mechanistic Findings in COPD
Year: 2017
The NLRP3 inflammasome pathway is activated in sarcoidosis and involved in granuloma formation
Source: Eur Respir J, 55 (3) 1900119; 10.1183/13993003.00119-2019
Year: 2020
Extracellular Hsp70 alters cigarette smoke-induced pro-inflammatory responses in human macrophages
Source: International Congress 2018 – Translational models of the immunopathology that underlies airway obstructive diseases
Year: 2018
Cigarette smoke induce Epithelial-Derived Inflammation through activating autophagy via RAGE signaling in bronchial epithelial cells.
Source: International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms
Year: 2019
Overexpression of CBP augments cigarette smoke-induced pro-inflammatory cytokine release in macrophages
Source: Eur Respir J 2005; 26: Suppl. 49, 105s
Year: 2005
Cigarette smoke induces CXCL8 production by human neutrophils via activation of TLR9 receptor
Source: Eur Respir J 2010; 36: 1143-1154
Year: 2010
NLRP3 inflammasome conjugates with mitochondria in LPS-induced acute lung injury
Source: Virtual Congress 2020 – Cellular stress in respiratory diseases
Year: 2020
Silica-induced inflammasome activation in lung epithelial cells
Source: Annual Congress 2012 - Abestosis, silicosis and hypersensitivity pneumonitis
Year: 2012
NDP52 inhibition rescues cigarette smoke mediated impairment of autophagy in macrophages
Source: International Congress 2016 – New therapies and therapeutic targets
Year: 2016
Cigarette smoking extracts stimulated human neutrophils to release neutrophil extracellular traps through a mitochondrial ROS-dependent way
Source: International Congress 2019 – Revealing novel asthma immunopathology endotypes
Year: 2019
RAGE blocking ameliorates cigarette smoke extract-induced human alveolar tpye II epithelial cell injury via RAGE-mediated redox sensitive DAMP signaling through Nrf2
Source: International Congress 2018 – COPD: immune regulation and therapeutic targets
Year: 2018
Cigarette smoke upregulates IL-8/CXCL8 expression by augmenting mRNA stability
via
p38 MAPK/MK2 signalling in normal human pulmonary cells
Source: Annual Congress 2012 - Basic and translational studies in COPD
Year: 2012
Cigarette smoke extracts decrease basal and lipopolysaccharide-induced expression of macrophage receptor with collagenous structure via degradation of p300
Source: International Congress 2018 – Disease exacerbations from a molecular point of view
Year: 2018
Curcumin restores glucocorticoid function and inhibits cigarette smoke-mediated IL-8 release in oxidant stressed monocytic U937 cells
Source: Eur Respir J 2005; 26: Suppl. 49, 215s
Year: 2005
Role of NLRP3 inflammasome and ATP in S100A12-induced MUC5AC production in airway epithelial cells
Source: International Congress 2018 – New kids on the block: novel molecular pathways and therapeutic targets in chronic lung diseases
Year: 2018
We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking "Accept", you consent to the use of the cookies.
Accept