Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis

A. Haak (Rochester, United States of America), E. Kostallari (Rochester, United States of America), D. Sicard (Rochester, United States of America), G. Ligresti (Rochester, United States of America), K. Choi (Rochester, United States of America), N. Caporarello (Rochester, United States of America), D. Jones (Rochester, United States of America), Q. Tan (Rochester, United States of America), J. Meridew (Rochester, United States of America), A. Diaz Espinosa (Rochester, United States of America), A. Aravamudhan (Rochester, United States of America), J. Maiers (Rochester, United States of America), R. Britt (Rochester, United States of America), A. Roden (Rochester, United States of America), C. Pabelick (Rochester, United States of America), Y. Prakash (Rochester, United States of America), S. Nouraie (Pittsburgh, United States of America), X. Li (Pittsburgh, United States of America), Y. Zhang (Pittsburgh, United States of America), D. Kass (Pittsburgh, United States of America), D. Lagares (Boston, United States of America), A. Tager (Boston, United States of America), X. Varelas (Boston, United States of America), V. Shah (Rochester, United States of America), D. Tschumperlin (Rochester, United States of America)

Source: International Congress 2019 – Damage and remodelling in pulmonary fibrosis
Session: Damage and remodelling in pulmonary fibrosis
Session type: Oral Presentation
Number: 2113
Disease area: Interstitial lung diseases

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A. Haak (Rochester, United States of America), E. Kostallari (Rochester, United States of America), D. Sicard (Rochester, United States of America), G. Ligresti (Rochester, United States of America), K. Choi (Rochester, United States of America), N. Caporarello (Rochester, United States of America), D. Jones (Rochester, United States of America), Q. Tan (Rochester, United States of America), J. Meridew (Rochester, United States of America), A. Diaz Espinosa (Rochester, United States of America), A. Aravamudhan (Rochester, United States of America), J. Maiers (Rochester, United States of America), R. Britt (Rochester, United States of America), A. Roden (Rochester, United States of America), C. Pabelick (Rochester, United States of America), Y. Prakash (Rochester, United States of America), S. Nouraie (Pittsburgh, United States of America), X. Li (Pittsburgh, United States of America), Y. Zhang (Pittsburgh, United States of America), D. Kass (Pittsburgh, United States of America), D. Lagares (Boston, United States of America), A. Tager (Boston, United States of America), X. Varelas (Boston, United States of America), V. Shah (Rochester, United States of America), D. Tschumperlin (Rochester, United States of America). Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis. 2113

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