TGFβ induced myofibroblast differentiation is independent of p38 activation, but requires TGFβR1 kinase activity and correlates with TGFβ-mediated SMAD signaling and TGFβ-responsive gene expression patterns in human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 718s Year: 2004
BMP-Smad1 target gene Wnt inhibitory factor 1 (WIF1) coordinates BMP and Wnt signaling activities in regulating lung development in vivo Source: Annual Congress 2010 - New mechanisms in lung development, acute and chronic lung diseases Year: 2010
Targeting the Hippo signaling pathway to enhance ex vivo lung epithelial tissue regeneration and maturation Source: International Congress 2019 – New mechanistic insights into pulmonary fibrosis Year: 2019
Enhanced efficiency of phenotypic transition of asthmatic fibroblasts depends on canonical and non-canonical TGFß/Smad signaling pathways Source: International Congress 2018 – Identification of therapeutic targets for asthma Year: 2018
AMPK signalling regulates Nrf2 localization and activity via sirtuins in a monocytic cell line Source: Annual Congress 2011 - Recent developments in COPD Year: 2011
Inhibition of VEGF blocks the activation of TGF-β1 through a PI3K/Akt signaling pathway in allergic airway disease of mice Source: Annual Congress 2007 - Current issues in airway physiology, pharmacology and monitoring Year: 2007
A differential role for ceramide kinase in antigen/FcεRI mediated mast cell activation and function Source: Eur Respir J 2006; 28: Suppl. 50, 231s Year: 2006
Korean Red Ginseng inhibits diesel exhaust particles-induced MUC5AC/B expression and inflammation through suppressing TLR4 and NF-kB signaling pathway in vitro and in vivo Source: International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms Year: 2019
Activation of WNT co-receptor LRP5 is required for WNT and TGF-ß1 induced fibroblast activation Source: Virtual Congress 2020 – Physiological and cellular mechanisms affecting pulmonary pathologies Year: 2020
Activation of protease-activated receptor 2 elicits epithelial-mesenchymal transition in HBE cells via ROS signaling Source: International Congress 2017 – Therapeutic approaches in lung disease Year: 2017
Glucocorticoids promote TGF-β signalling in lung fibroblasts by upregulating ligand and receptor expression, and uncoupling negative-feedback inhibition Source: Annual Congress 2010 - Recent developments of molecular pathology and functional genomics in non-neoplastic and neoplastic lung diseases Year: 2010
Endothelin-1 activates pro-inflammatory signalling pathway via destinct p38MAPK isoforms resulting in downregulation of nuclear p27kip1 Source: Annual Congress 2009 - Airway cell biology Year: 2009
YI02 - Activation of Wnt/beta-catenin signaling promotes lung epithelial repair in emphysema Source: Lung Science Conference 2012 - Rebuilding a diseased lung: Repair and regeneration Year: 2012
Involvement of Hedgehog pathway in airway cell differentiation Source: International Congress 2018 – New kids on the block: novel molecular pathways and therapeutic targets in chronic lung diseases Year: 2018
Hypoxia induces IL-1β and TNF-α expressionin of U937 cells involving PKCα/RAF-1/MAPK/NF-κB pathway Source: Eur Respir J 2005; 26: Suppl. 49, 102s Year: 2005
Leptin activates the JAK/STAT signaling pathway in bronchial and alveolar epithelial cells Source: Eur Respir J 2006; 28: Suppl. 50, 338s Year: 2006
Thrombin induces epithelial-mesenchymal transition via PAR1, PKC and ERK1/2 pathways in A549 cells Source: Annual Congress 2012 - Diffuse parenchymal lung disease pathogenesis, biomarkers, therapy and new entities Year: 2012
Follistatin-like 1 promotes intermittent hypoxia-induced lung fibroblast activation in vitro and in vivo Source: International Congress 2019 – Immune-mediated interstitial lung diseases: from bench to bedside Year: 2019
Notch activity is required for myofibroblast differentiation Source: International Congress 2019 – Oxidative stress, hypoxia and microbial exposure in the pathogenesis of pulmonary disease Year: 2019