Trends of testing for and diagnosis of a1-antitrypsin deficiency in the UK: more testing is needed

Joan B. Soriano, Sarah J. Lucas, Rupert Jones, Marc Miravitlles, Victoria Carter, Iain Small, David Price, Ravi Mahadeva

Source: Eur Respir J, 52 (1) 1800360; 10.1183/13993003.00360-2018
Journal Issue: July
Disease area: Airway diseases

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Joan B. Soriano, Sarah J. Lucas, Rupert Jones, Marc Miravitlles, Victoria Carter, Iain Small, David Price, Ravi Mahadeva. Trends of testing for and diagnosis of a1-antitrypsin deficiency in the UK: more testing is needed. Eur Respir J, 52 (1) 1800360; 10.1183/13993003.00360-2018

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Challenges in interpreting trends in testing for a1-antitrypsin deficiency in COPD patients from UK primary care
Source: Eur Respir J, 52 (6) 1802064; 10.1183/13993003.02064-2018
Year: 2018



Challenges in interpreting trends in testing for a1-antitrypsin deficiency in COPD patients from UK primary care
Source: Eur Respir J, 52 (6) 1801986; 10.1183/13993003.01986-2018
Year: 2018



Molecular diagnosis of tuberculosis in a north Italian clinical setting: results of routine use of a commercial LCR-based test
Source: Eur Respir J 2001; 18: Suppl. 33, 360s
Year: 2001

Tuberculosis patients with unknown HIV status in the Netherlands: analysing underreporting and lack of testing
Source: Eur Respir J, 50 (5) 1701257; 10.1183/13993003.01257-2017
Year: 2017



Diagnosis and management of a1-antitrypsin deficiency in Europe: an expert survey
Source: ERJ Open Res, 5 (1) 00171-2018; 10.1183/23120541.00171-2018
Year: 2019



Electrophoresis of blood serum: A helpful diagnostic tool for identifying respiratory patients with alpha1-antitrypsin deficiency
Source: International Congress 2015 – Translational research in respiratory care: new findings
Year: 2015


Testing for Alfa1-antitrypsin deficiency: is phenotyping enough?
Source: International Congress 2019 – Epidemiology, genetics, air pollution and sleep
Year: 2019


Conversion of tuberculosis screening tests during biological therapy in patients with rheumatic diseases: what’s beyond screening values?
Source: International Congress 2018 – Tuberculosis transmission and screening strategies
Year: 2018



Clinical exercise testing with reference to lung diseases: indications, standardization and interpretation strategies
Source: Guideline 1997
Year: 1997

National roll-out of latent tuberculosis testing and treatment for new migrants in England: a retrospective evaluation in a high-incidence area
Source: Eur Respir J, 51 (1) 1701226; 10.1183/13993003.01226-2017
Year: 2018



Interpretation of indeterminate RIF-susceptibility results obtained by rapid molecular diagnostics test
Source: International Congress 2016 – Rifampicin resistance, MDRTB, and new drug treatments
Year: 2016

Age-Adjusted D-Dimer Cut Off: Could this prove cost-effective and safe for our Emergency Units?Authors:Mills M, Downey C ,  Townley S, Kasis A, Dutt T, Gautam M.Introduction:A D-dimer test result (conventionally up to 500 µg/L) is an important component of the diagnostic work-up for patients with suspected VTE, however, it is well known that D-Dimer levels rise with age. Although a negative D-Dimer in conjunction with a clinical probability score can be effective at excluding DVT/PE, studies have proposed that the use of an age-adjusted cut off can increase the number of patients excluded from further testing with a low likelihood of subsequent VTE.This study looked at unselected D-dimer requests from the Emergency department (ED) for patients with suspected DVT/PE to assess the potential impact of introducing age-adjusted D-dimer cut off limits.
Source: International Congress 2017 – Prognostic factors and outcomes in pulmonary embolism
Year: 2017

Cardiac sarcoidosis: screening, diagnosis and treatment
Source: International Congress 2019 – State of the art session: Interstitial lung diseases
Year: 2019


Tuberculosis screening of migrants to low-burden nations: insights from evaluation of UK practice
Source: Eur Respir J 2011; 37: 1175-1182
Year: 2011



Clinical phenotype of individuals with common COPD investigated during the targeted detection programme for alpha1-antitrypsin deficiency in Italy
Source: Annual Congress 2007 - Clinical aspects in COPD
Year: 2007


Assessment of the effect of community spirometry testing on diagnosis and management
Source: Eur Respir J 2005; 26: Suppl. 49, 62s
Year: 2005

Evidence assessment on the use of IGRA testing in diagnosing latent tuberculosis – A TBNET review
Source: Annual Congress 2010 - Interferon-gamma releases assays (IGRAs) for the diagnosis of tuberculosis: what is the role?
Year: 2010


Evidence assessment on the use of IGRA testing in diagnosing active tuberculosis: A systematic TBNET review
Source: Annual Congress 2010 - Interferon-gamma releases assays (IGRAs) for the diagnosis of tuberculosis: what is the role?
Year: 2010

The Irish national alpha-1 antitrypsin deficiency targeted detection programme
Source: Annual Congress 2013 –Epidemiology of respiratory disease
Year: 2013


Diagnosis of osteoporosis in adult CF patients: the need for careful evaluation
Source: Eur Respir J 2001; 18: Suppl. 33, 539s
Year: 2001