ER stress is involved in alveolar epithelial cell dysfunction in hypoxia

e. Delbrel (Bobigny, France), A. Soumare (Bobigny, France), D. Marchant (Bobigny, France), T. Gille (Bobigny, France), J. Bernaudin (Bobigny, France), C. Planès (Bobigny, France), E. Boncoeur (Bobigny, France)

Source: International Congress 2018 – Back to basics and translational research in idiopathic interstitial pneumonias
Session: Back to basics and translational research in idiopathic interstitial pneumonias
Session type: Thematic Poster
Number: 4809
Disease area: Interstitial lung diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
e. Delbrel (Bobigny, France), A. Soumare (Bobigny, France), D. Marchant (Bobigny, France), T. Gille (Bobigny, France), J. Bernaudin (Bobigny, France), C. Planès (Bobigny, France), E. Boncoeur (Bobigny, France). ER stress is involved in alveolar epithelial cell dysfunction in hypoxia. 4809

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Cadmium-induced inflammation and ER stress are mediated through C/EBP-DDIT3 signaling in human bronchial epithelial cells
Source: International Congress 2017 – Insight into the pathogenesis of emphysema and pneumonia
Year: 2017

Distinct profile of oxidative stress-induced cell death of normal and cystic fibrosis airway epithelial cells
Source: Eur Respir J 2004; 24: Suppl. 48, 106s
Year: 2004

Enhancement of the airway epithelial cell response to dsRNA by oxidative stress
Source: Annual Congress 2008 - Airway cell biology
Year: 2008

Cigarette-decreased NAD/SIRT1 aggravates pulmonary fibrosis by promoting senescence of alveolar type 2 cells through autophagy inhibition and mitochondrial oxidative stress induction
Source: Virtual Congress 2020 – Idiopathic pulmonary fibrosis and interstitial lung disease: progression, genes and more
Year: 2020

Apoptosis and non-apoptotic cell death induced by mechanical stress in alveolar type II cells and pulmonary microvascular endothelial cells
Source: Eur Respir J 2003; 22: Suppl. 45, 587s
Year: 2003

Hypoxia-induced cytoskeleton disruption in alveolar epithelial cells
Source: Annual Congress 2007 - Respiratory pathophysiology
Year: 2007



Extracellular vesicles produced by airway epithelial cells in response to oxidative stress contain microRNAs associated with cellular senescence
Source: Virtual Congress 2021 – Cellular and molecular involvement in lung injury and repair
Year: 2021



Alpha1-Antitrypsin reduces endoplasmic reticulum stress, inflammatory cytokines and improves wound repair in alveolar epithelial cells of fibrotic lung in vitro
Source: International Congress 2017 – Cellular signalling pathways in pulmonary fibrosis
Year: 2017

Mitochondrial antioxidants decrease oxidative stress and inflammation induced bronchial epithelial cell line
Source: International Congress 2016 – Studies in airway cell biology
Year: 2016


Oxidative stress enhances expression of extracellular matrix proteins in bronchial epithelial cells
Source: Eur Respir J 2007; 30: Suppl. 51, 219s
Year: 2007

Cigarette smoke-induced activation of the integrated stress response in COPD airway epithelial cells and the role of oxidative stress
Source: International Congress 2018 – New kids on the block: novel molecular pathways and therapeutic targets in chronic lung diseases
Year: 2018

Acetylcholine leads to STAT-1 mediated oxidative/nitrosative stress in human bronchial epithelial cells
Source: Annual Congress 2012 - Cellular signalling mechanisms in the airways
Year: 2012


LSC Abstract – Alpha1-antitrypsin reduces inflammation and endoplasmic reticulum stress in lung epithelial cells in vitro
Source: International Congress 2015 – Cellular and molecular mechanisms of COPD and emphysema
Year: 2015

Dehydrocostuslactone-induced apoptosis through oxidative and endoplasmic reticulum stress signaling in human non-small cell lung cancer cells
Source: Annual Congress 2010 - Pathology of lung cancer
Year: 2010


Inhibition of ER stress suppresses IL-13 induced airway epithelial remodeling
Source: International Congress 2019 – COPD, asthma and rhinitis: from cellular mechanisms to patients’ clinical responses
Year: 2019

Chronic WNT/ß-catenin signaling impairs mitochondrial function in lung epithelial cells
Source: Virtual Congress 2021 – Cellular and molecular involvement in lung injury and repair
Year: 2021



Resistance of quiescent and proliferating airway epithelial cells to H2O2 challenge
Source: Eur Respir J 2007; 29: 633-642
Year: 2007



Epithelial fibroblast triggering and interactions in pulmonary fibrosis
Source: Eur Respir Rev 2008; 17: 123-129
Year: 2008



PTEN deficiency in alveolar type 2 cells accelerates cellular senescence, disrupts epithelial–mesenchymal and mitochondrial homeostasis, and induces age-related emphysema
Source: International Congress 2019 – Cellular metabolism and immune senescence in lung pathology
Year: 2019



Physical stress modulates distal lung tissue mechanics, inflammation and remodelling associated to iNOS and oxidative stress activation
Source: Annual Congress 2008 - Pathophysiology of respiratory diseases
Year: 2008