Efficacy of combined therapy with pirfenidone and inhaled N-acetylcysteine for idiopathic pulmonary fibrosis: a randomized controlled phase 3 trial
S. Homma (Tokyo, Japan), Y. Kondoh (Aichi, Japan), M. Kato (Tokyo, Japan), T. Hoshino (Fukuoka, Japan), H. Mukae (Nagasaki, Japan), M. Bando (Tochigi, Japan), T. Suda (Hamamatsu, Japan), T. Kido (Fukuoka, Japan), Y. Tanino (Fukushima, Japan), T. Kishaba (Okinawa, Japan), N. Hattori (Hiroshima, Japan), Y. Taguchi (Nara, Japan), T. Saitoh (Ibaraki, Japan), Y. Nishioka (Tokushima, Japan), K. Kuwano (Tokyo, Japan), K. Kishi (Tokyo, Japan), N. Inase (Tokyo, Japan), S. Sasaki (Chiba, Japan), H. Takizawa (Tokyo, Japan), T. Johkoh (Osaka, Japan), F. Sakai (Saitama, Japan), S. Sakamoto (Tokyo, Japan)
Source: International Congress 2018 – Management of idiopathic interstitial pneumonias: established and new treatments
Disease area: Interstitial lung diseases
Rating:
You must login to grade this presentation.
Share or cite this content
Citations should be made in the following way:
S. Homma (Tokyo, Japan), Y. Kondoh (Aichi, Japan), M. Kato (Tokyo, Japan), T. Hoshino (Fukuoka, Japan), H. Mukae (Nagasaki, Japan), M. Bando (Tochigi, Japan), T. Suda (Hamamatsu, Japan), T. Kido (Fukuoka, Japan), Y. Tanino (Fukushima, Japan), T. Kishaba (Okinawa, Japan), N. Hattori (Hiroshima, Japan), Y. Taguchi (Nara, Japan), T. Saitoh (Ibaraki, Japan), Y. Nishioka (Tokushima, Japan), K. Kuwano (Tokyo, Japan), K. Kishi (Tokyo, Japan), N. Inase (Tokyo, Japan), S. Sasaki (Chiba, Japan), H. Takizawa (Tokyo, Japan), T. Johkoh (Osaka, Japan), F. Sakai (Saitama, Japan), S. Sakamoto (Tokyo, Japan). Efficacy of combined therapy with pirfenidone and inhaled N-acetylcysteine for idiopathic pulmonary fibrosis: a randomized controlled phase 3 trial. 4795
You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.
Member's Comments
Related content which might interest you:
Related content which might interest you:
Pirfenidone plus inhaled N-acetylcysteine for idiopathic pulmonary fibrosis: a randomised trial Source: Eur Respir J, 57 (1) 2000348; 10.1183/13993003.00348-2020 Year: 2021
Macitentan for the treatment of idiopathic pulmonary fibrosis: the randomised controlled MUSIC trial Source: Eur Respir J 2013; 42: 1622-1632 Year: 2013
Azithromycin for the treatment of cough in idiopathic pulmonary fibrosis: A randomized controlled cross-over pilot trial. Source: Virtual Congress 2020 – Chronic cough: only symptom or disease? Year: 2020
RCT Abstract - Cyclophosphamide added to glucocorticoids in acute exacerbation of idiopathic pulmonary fibrosis (EXAFIP): a randomized, double-blind, placebo-controlled, phase 3 trial Source: Virtual Congress 2021 – ALERT: Asthma in adult, in children and ILDs Year: 2021
Inhaled beclomethasone/formoterol in idiopathic pulmonary fibrosis: a randomised controlled exploratory study Source: ERJ Open Res, 3 (4) 00100-2017; 10.1183/23120541.00100-2017 Year: 2017
Inhaled budesonide in the treatment of early COVID-19 illness: a randomised controlled trial Source: Virtual Congress 2021 – ALERT: bronchiectasis and COVID Year: 2021
Concomitant corticosteroid with anti-fibrotic therapy for idiopathic pulmonary fibrosis: a prospective multicenter study Source: Virtual Congress 2021 – News in treatment and diagnosis of idiopathic interstitial pneumonia Year: 2021
A randomized, double-blind, placebo-controlled, phase III study of the safety and efficacy of interferon gamma-1b in patients with idiopathic pulmonary fibrosis Source: Annual Congress 2007 - Clinical trial: new biological approaches to respiratory diseases Year: 2007
Omalizumab in patients with moderate-to-severe persistent asthma poorly controlled on high-dose inhaled corticosteroids and long-acting beta-agonists: Results of a phase IIIb randomized controlled trial Source: Annual Congress 2010 - Aspects of severe asthma Year: 2010
Recent clinical trials in idiopathic pulmonary fibrosis and the BUILD-1 study Source: Eur Respir Rev 2008; 17: 116-122 Year: 2008
Effects of combined therapy with nebulized b2 -agonist and anticholinergic in severe exacerbation of chronic obstructive pulmonary disease. Randomized controlled trial Source: Eur Respir J 2007; 30: Suppl. 51, 611s Year: 2007
Randomized controlled trial of nebulized budesonide suspension in acute severe exacerbation of COPD Source: Eur Respir J 2002; 20: Suppl. 38, 244s Year: 2002
High-dose versus low-dose prednisolone in symptomatic patients with post-COVID-19 diffuse parenchymal lung abnormalities: an open-label, randomised trial (the COLDSTER trial) Source: Eur Respir J, 59 (2) 2102930; 10.1183/13993003.02930-2021 Year: 2022
Effect of high-flow oxygen therapy on exercise tolerance in idiopathic pulmonary fibrosis: a randomized crossover trial. Source: Virtual Congress 2021 – Best abstracts in pulmonary rehabilitation and chronic care Year: 2021
Efficacy and safety of combined use of pirfenidone and nintedanib in patients with idiopathic pulmonary fibrosis Source: Virtual Congress 2021 – News in treatment and diagnosis of idiopathic interstitial pneumonia Year: 2021
The effect of low-dose corticosteroids and theophylline on the risk of acute exacerbations of COPD: the TASCS randomised controlled trial Source: Eur Respir J, 57 (6) 2003338; 10.1183/13993003.03338-2020 Year: 2021
Evaluation of ICS/LABA combination therapy on respiratory function in patients with asthma: Open-label, randomized, cross-over trial. Source: International Congress 2018 – New developments in the treatment of asthma Year: 2018
Efficacy and safety of single-inhaler triple therapy of glycopyrronium, formoterol and fluticasone in patients with COPD: a double-blind, randomised controlled trial Source: ERJ Open Res, 7 (3) 00255-2021; 10.1183/23120541.00255-2021 Year: 2021
Budesonide versus prednisone in acute wheezing: randomized double-blinded controlled placebo study Source: Annual Congress 2008 - Treatment and outcome of childhood asthma: new perspectives Year: 2008