Neutrophil extracellular traps promoted alveolar macrophages pyroptosis in LPS induced ALI/ARDS

H. Lee (Changsha, China), P. Pan (Changsha, China)

Source: International Congress 2018 – Role of microbial exposure and inflammation in lung injury
Session: Role of microbial exposure and inflammation in lung injury
Session type: Thematic Poster
Number: 4284
Disease area: Respiratory critical care

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
H. Lee (Changsha, China), P. Pan (Changsha, China). Neutrophil extracellular traps promoted alveolar macrophages pyroptosis in LPS induced ALI/ARDS. 4284

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Impaired efferocytosis and neutrophil extracellular trap clearance by macrophages in ARDS
Source: Eur Respir J, 52 (2) 1702590; 10.1183/13993003.02590-2017
Year: 2018



Neutrophil extracellular trap formation is regulated by CXCR2 in COPD neutrophils
Source: Eur Respir J, 51 (4) 1700970; 10.1183/13993003.00970-2017
Year: 2018



Hypoxia induces IL-18 and neutrophil influx in lung parenchyma possibly mediated by MIP-2
Source: Annual Congress 2012 - The many roads to lung injury
Year: 2012

Resveratrol impairs the release of steroid-resistant cytokines from bacterial endotoxin-exposed alveolar macrophages (AM) in COPD
Source: Annual Congress 2011 - Experimental modulation of airway inflammation
Year: 2011

Impaired Alveolar Macrophage Efferocytosis in ARDS causes accumulation of apoptotic neutrophils & prolonged inflammation
Source: International Congress 2018 – Role of microbial exposure and inflammation in lung injury
Year: 2018

Increased production of caspase-1 by alveolar macrophages in patients with pulmonary sarcoidosis
Source: Eur Respir J 2002; 20: Suppl. 38, 585s
Year: 2002

Oxidative burst in lipopolysaccharide-activated human alveolar macrophages is inhibited by interleukin-9
Source: Eur Respir J 2002; 20: 1198-1205
Year: 2002



Increased SDF-1alpha production from alveolar macrophages in sarcoidosis in vitro
Source: Annual Congress 2008 - Sarcoidosis: pathophysiology and severity
Year: 2008

Azithromycin increases phagocytosis of apoptotic airway epithelial cells by alveolar macrophages in vitro
Source: Annual Congress 2005 - Cellular and molecular approaches to lung injury research
Year: 2005


Compartmentalized neutrophil recruitment and matrix metalloprotease (MMP)-9 release after airway exposure to endotoxin in humans
Source: Eur Respir J 2004; 24: Suppl. 48, 554s
Year: 2004

LSC - 2018 - Differential effect of ARDS on alveolar macrophage efferocytosis compared to bacterial phagocytosis
Source: International Congress 2018 – Role of microbial exposure and inflammation in lung injury
Year: 2018

Prostaglandin-E2 mediated inhibition of TNFα release from human alveolar macrophages
Source: Eur Respir J 2005; 26: Suppl. 49, 223s
Year: 2005

Neutrophil extracellular traps contribute to pulmonary fibrosis induced by bleomycin
Source: International Congress 2019 – New mechanistic insights into pulmonary fibrosis
Year: 2019

Alveolar macrophage activity in experimentally induced pneumonia
Source: Annual Congress 2012 - Lung injury and repair: reactive oxygen species and beyond
Year: 2012

Increased in vitro production of IP-10/CXCL10 and MIG/CXCL9 by alveolar macrophages in sarcoidosis and EAA but not in IPF
Source: Annual Congress 2008 - Role of bronchoalveolar lavage in studying the pathophysiology of interstitial lung disease
Year: 2008

Rhinovirus induces airway fibroblast release of neutrophil but not eosinophil chemokines
Source: Annual Congress 2005 - Host-pathogen interaction in respiratory virus infections
Year: 2005


Azithromycin increases phagocytosis of apoptotic bronchial epithelial cells by alveolar macrophages
Source: Eur Respir J 2006; 28: 486-495
Year: 2006



Protein S inhibits the secretion of inflammatory cytokines from alveolar epithelial cells
Source: Annual Congress 2008 - Structural remodelling in COPD
Year: 2008

Role of alveolar epithelial ICAM-1 in lipopolysaccharide-induced lung inflammation
Source: Eur Respir J 2002; 19: 1142-1150
Year: 2002



BALF modulates neutrophil phagocytosis and ROS production in different ways
Source: Annual Congress 2009 - Airway inflammation and host defence
Year: 2009