cPLA2alpha inhibitor ASB14780 suppresses airway MMP-9 production and improves respiratory function in cigarette-smoke induced model Source: International Congress 2014 – Animal models in respiratory drug development Year: 2014
Macrolide effects on the prevention of COPD exacerbations Source: Eur Respir J 2012; 40: 485-494 Year: 2012
Characterisation of a model that mimics aspects of the hyper-inflammatory response observed during an acute exacerbation of COPD. Source: Research Seminar 2009 - Molecular and Cellular aspects of Chronic Lung Disease Year: 2009
Increased small intestinal permeability during severe acute exacerbations of COPD Source: International Congress 2016 – Non-inflammatory COPD monitoring Year: 2016
Targeting the mTOR signaling pathway to inhibit lung cell senescence in chronic obstructive pulmonary disease (COPD) Source: ERS Lung Science Conference 2017 Year: 2017
Aerobic training reverses the inhibition in the expression of glucocorticoid receptors and decreases the Th2 allergic inflammation in asthma model Source: Annual Congress 2013 –The multiple faces of stress in lung injury Year: 2013
Inhaled formulation of angiotensin-(1-7) produces lung protective effects in a model of chronic asthma. Source: International Congress 2018 – Identification of therapeutic targets for asthma Year: 2018
AZD7624, an inhaled p38 inhibitor for COPD, attenuates lung and systemic inflammation after LPS Challenge in humans Source: International Congress 2015 – Advances in the future treatment of COPD Year: 2015
Dual mechanism of action of T2 inhibitor therapies in virally induced exacerbations of asthma: evidence for a beneficial counter-regulation Source: Eur Respir J, 54 (1) 1802390; 10.1183/13993003.02390-2018 Year: 2019
Effect of mast cells degranulation blockade on the inflammatory response outcome in the COPD model Source: International Congress 2016 – New signalling pathways in COPD Year: 2016
The effect of leukotrienes receptor antagonists on lung function, exercise tolerance and incidence of exacerbations in patients with stable, moderate COPD Source: Eur Respir J 2002; 20: Suppl. 38, 620s Year: 2002
Activation of the β-catenin pathway by Wnt-1 treatment suppress inflammation in the mouse model of allergic airway disease Source: International Congress 2015 – Advances in asthma and allergy in animal models Year: 2015
Inhibition of phosphodiesterase 4B enhances glucocorticoid-dependent gene transcription in human airway epithelial cells: Implications for the treatment of COPD Source: Annual Congress 2013 –New drugs in respiratory medicine Year: 2013
MIF antagonism restores corticosteroid sensitivity in a murine model of severe asthma Source: International Congress 2018 – Identification of therapeutic targets for asthma Year: 2018
Mechanisms of vascular endothelial cell injury in response to intermittent and continuous hypoxia exposure and protective effects of anti-inflammatory and anti-oxidant agents Source: International Congress 2019 – Novel methods, diagnostics and biomarkers in chronic lung diseases Year: 2019
Selective activation and targeting of autophagy in severe asthma. Source: International Congress 2018 – Preclinical pharmacology: novel targets in airway inflammation, narrowing and neural control Year: 2018
Inhibitory effect of statins on fibrogenic mediator production from lung cells Source: Annual Congress 2012 - Diffuse parenchymal lung disease pathogenesis, biomarkers, therapy and new entities Year: 2012
Anti-inflammatory effects of targeted lung denervation in patients with COPD Source: Eur Respir J 2015; 46: 1489-1492 Year: 2015
Neu-164, a novel antioxidant and anti-inflammatory compound reduces lung inflammation in a murine model of allergic asthma Source: Annual Congress 2008 - Comorbid cardiovascular condition and therapy of asthma Year: 2008
PF-03715455: An inhaled p38 inhibitor for the treatment of chronic obstructive pulmonary disease Source: Annual Congress 2013 –Novel drugs for the treatment of asthma and COPD Year: 2013