Low FFMI in COPD patients undergoing pulmonary rehabilitation T. Hafner (golnik, Slovenia), I. Sarc (golnik, Slovenia), A. Groselj (golnik, Slovenia), Z. Zdolsek (golnik, Slovenia), B. Zupanc (golnik, Slovenia), T. Kosten (golnik, Slovenia)
Source: International Congress 2018 – Pulmonary rehabilitation: exercise training, body composition, physical activity and other aspects
Disease area: Airway diseasesAbstract
Low FFMI
Normal FFMI
p value
Age
65.8 ±7.8
64.5 ±7.3
0.31
FEV1 % pred
34±13
45±17
0.001
SGRQ baseline
38± 14
32±13
0.032
SGRQ after PR
33.3±13.3
27±12.6
0.028
SGRQ difference
5.3±6.6
4.9±6.6
0.85
6MWT baseline
332±113
373±106
0.134
6MWT after PR
388±106
440±100
0.077
6MWT difference
53±54
59±59
0.87
Introduction: In patients with COPD fat-free mass index (FFMI) predicts survival, but implications of low FFMI according to ESPEN criteria on outcomes of pulmonary rehabilitation (PR) are less well known. The aim of our study was to determine the prevalence of low FFMI in PR program and compare groups of normal and low FFMI.
Methods: We analysed retrospectivelly collected cohort of consecutive COPD patients undergoing PR. Body composition was assessed by multi- frequency bioelectrical impedance analysis. Low fat-free mass index (FFMI) was defined as <17 kg/m2 for males and < 15 kg/m2 for females according to ESPEN criteria. Quality of life was assessed with St. George's Respiratory Questionnaire (SGRQ), all patients performed 6 minute walk test (6MWT).
Results: Final sample included 100 patients (age 65 ±7.6, FEV1 39 ± 16% predicted, 59% men, BMI 25.1 ±6kg/m2). Low FFMI was found in 54 (54%) patients. The two subgroups (low vs. normal FFMI) showed statistically significant differences only in FEV1 % predicted and SGRQ at baseline (Table1). Both groups improved SGRQ and 6MWT after PR clinically and statistically significantly (p<0.001 for both).
Conclusions: Low FFMI was frequent. Low FFMI group had more advanced COPD and lower quality of life, but baseline 6MWT did not differ significantly. Low FFMI did not impair 6MWT and SGRQ improvement due to PR, both groups improved clinically significantly to a similar degree.
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T. Hafner (golnik, Slovenia), I. Sarc (golnik, Slovenia), A. Groselj (golnik, Slovenia), Z. Zdolsek (golnik, Slovenia), B. Zupanc (golnik, Slovenia), T. Kosten (golnik, Slovenia). Low FFMI in COPD patients undergoing pulmonary rehabilitation. 4125
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