Endothelin-1-induced airway and parenchymal mechanical responses in guinea-pigs: the roles of ETA and ETB receptors

Adamicza A., Petak F., Asztalos T., Tiszlavicz L., Boros M., Hantos Z.

Source: Eur Respir J 2001; 17: 975-981
Journal Issue: May
Disease area: Airway diseases

Congress or journal article abstractPDF journal article, handout or slidesFull text journal article

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Adamicza A., Petak F., Asztalos T., Tiszlavicz L., Boros M., Hantos Z.. Endothelin-1-induced airway and parenchymal mechanical responses in guinea-pigs: the roles of ETA and ETB receptors. Eur Respir J 2001; 17: 975-981

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Role of airway smooth muscles in chronic airway inflammation and lung fibrosis and possible therapeutic potential of endothelin receptor antagonism
Source: Annual Congress 2010 - New mechanisms in lung development, acute and chronic lung diseases
Year: 2010

The inflammatory response of pulmonary vascular smooth muscle cells to bacterial endotoxin is sensitive to endothelin receptor antagonism
Source: Annual Congress 2012 - Phenotypes and mechanisms of treatment of asthma
Year: 2012

Bosentan inhibits cigarette smoke-induced endothelin receptor expression in pulmonary arteries
Source: Eur Respir J 2012; 39: 927-938
Year: 2012



Role of muscarinic receptors in airway inflammation and remodelling
Source: International Congress 2015 – Respiratory research in the Netherlands
Year: 2015


Endothelin-1 receptor antagonists prevent the development of pulmonary emphysema in rats
Source: Eur Respir J 2010; 35: 904-912
Year: 2010



Endothelin receptor expression in idiopathic pulmonary arterial hypertension: effect of bosentan and epoprostenol treatment
Source: Eur Respir J 2011; 38: 851-860
Year: 2011



Fevipiprant reduces airway smooth muscle mass in asthmatics via PGD2 receptor antagonism
Source: International Congress 2017 – Novel mechanisms and treatments for asthma
Year: 2017




Is there a role for endothelin-1 receptor antagonists in the treatment of lung fibrosis associated with pulmonary hypertension?
Source: Eur Respir J, 52 (2) 1801287; 10.1183/13993003.01287-2018
Year: 2018



Modulation of bleomycin-induced lung fibrosis by serotonin receptor antagonists in mice
Source: Eur Respir J 2008; 32: 426-436
Year: 2008



Discrepant distribution of big endothelin (ET)-1 and ET receptors in the pulmonary artery
Source: Eur Respir J 2001; 18: 5-14
Year: 2001



Endothelin receptor antagonists in pulmonary arterial hypertension
Source: Eur Respir J 2008; 31: 407-415
Year: 2008



Blocking endothelin: breaking new ground
Source: Eur Respir Rev 2008; 17: 24-29
Year: 2007



Endothelin receptor antagonists (ERAs) neutralize LPS-induced cytokine release from pulmonary vascular smooth muscle cells (PVSMCs) by down-regulation of CD14
Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Year: 2013

Comparison of glucocorticoid and cysteinyl leukotriene receptor antagonist treatments in the airway remodeling induced by chronic airway inflammation in guinea pigs
Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD II
Year: 2008

The role of purinergic P2X7 receptors on lipopolysaccharide (LPS)-induced lung injury
Source: Annual Congress 2007 - Acute and chronic lung injury and its repair: novel molecular insight
Year: 2007



Discovery of competitive thromboxane receptor (TP) antagonism by diclofenac in guinea pig airway and vascular tissues
Source: Annual Congress 2007 - Recent advances in airway smooth muscle biology
Year: 2007


Endothelin-1 receptor antagonist prevents hyperoxia-induced parenchymal mechanical impairment in mice
Source: Eur Respir J 2004; 24: Suppl. 48, 334s
Year: 2004

A role of prostaglandin D2 receptor, CRTH2, on bleomycin-induced pulmonary fibrosis
Source: Annual Congress 2008 - Understanding allergic airway inflammation with the help of animal models
Year: 2008

Optimization of tissue targeting properties of macitentan, a new dual endothelin receptor antagonist, improves its efficacy in a rat model of pulmonary fibrosis associated with pulmonary arterial hypertension
Source: Annual Congress 2011 - Treatment of human pulmonary hypertension
Year: 2011


Increased relaxation of immature airways to beta-2 agonists is related to the attenuated expression of postjunctional smooth muscle muscarinic M2 receptors
Source: Annual Congress 2004 - Understanding the complexity of how airways are regulated
Year: 2004