A European regulatory perspective on cystic fibrosis: current treatments, trends in drug development and translational challenges for CFTR modulators

Stefano Ponzano, Giulia Nigrelli, Laura Fregonese, Irmgard Eichler, Fabio Bertozzi, Tiziano Bandiera, Luis J.V. Galietta, Marisa Papaluca

Source: Eur Respir Rev, 27 (148) 170124; 10.1183/16000617.0124-2017
Journal Issue: June

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Stefano Ponzano, Giulia Nigrelli, Laura Fregonese, Irmgard Eichler, Fabio Bertozzi, Tiziano Bandiera, Luis J.V. Galietta, Marisa Papaluca. A European regulatory perspective on cystic fibrosis: current treatments, trends in drug development and translational challenges for CFTR modulators. Eur Respir Rev, 27 (148) 170124; 10.1183/16000617.0124-2017

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
ENaC inhibition in cystic fibrosis: potential role in the new era of CFTR modulator therapies
Source: Eur Respir J, 56 (6) 2000946; 10.1183/13993003.00946-2020
Year: 2020



The era of CFTR modulators: improvements made and remaining challenges
Source: Breathe, 16 (2) 200016; 10.1183/20734735.0016-2020
Year: 2020



CFTR targeted therapies: recent advances in cystic fibrosis and possibilities in other diseases of the airways
Source: Eur Respir Rev, 29 (156) 190068; 10.1183/16000617.0068-2019
Year: 2020



Progress in precision medicine in cystic fibrosis: a focus on CFTR modulator therapy
Source: Breathe, 17 (4) 210112; 10.1183/20734735.0112-2021
Year: 2021



Gene therapy for cystic fibrosis: successes and challenges
Source: ISSN=ISSN 1025-448x, ISBN=ISBN 1-904097-46-6, page=79
Year: 2006

The cystic fibrosis transmembrane conductance regulator and its modulators: clinical implications
Source: Virtual Congress 2020 – Respiratory infections
Year: 2020


Treatment of interstitial lung diseases: current approaches and future directions
Source: Virtual Congress 2021 – Interstitial lung diseases: from disease mechanisms to novel treatment options
Year: 2021


COPD mechanisms: novel aspects and implications for new therapies
Source: ERS Live 2007
Year: 2007


Idiopathic pulmonary fibrosis: current challenges and future perspectives
Source: Eur Respir Rev 2013; 22: 103-105
Year: 2013


Targeting a genetic defect: cystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis
Source: Eur Respir Rev 2013; 22: 58-65
Year: 2013



How organoids helped to discover cystic fibrosis transmembrane conductance regulator (CFTR) therapeutics and predict response to treatment
Source: International Congress 2016 – Closing the gap: novel translational research strategies
Year: 2016


Pharmacotherapy for idiopathic pulmonary fibrosis: current landscape and future potential
Source: Eur Respir Rev, 26 (145) 170071; 10.1183/16000617.0071-2017
Year: 2017



Can different approaches to anti-inflammatory therapy result in different outcomes in cystic fibrosis patients?
Source: Annual Congress 2007 - Cystic fibrosis lung disease: what do we measure? What do we know?
Year: 2007


Genomically-guided therapies: a new era for cystic fibrosis
Source: Virtual Congress 2020 – European Reference Network for rare lung diseases (ERN-LUNG): acting for improved cross-border management of rare diseases
Year: 2020


Possible mechanisms of action of azithromycin in cystic fibrosis
Source: Annual Congress 2005 - Cystic fibrosis lung disease: pieces of the puzzle
Year: 2005


Pharmacological treatment of the biochemical defect in cystic fibrosis airways
Source: Eur Respir J 2001; 17: 1314-1321
Year: 2001



CF clinical care and its delivery: current and future challenges
Source: International Congress 2019 – Future of cystic fibrosis care: insights from the Lancet Commission
Year: 2019