Attenuation by oral N-acetylcysteine of bleomycin-induced lung injury in rats

Cortijo J., Cerda-Nicolas M., Serrano A., Bioque G., Estrela J.M., Santangelo F., Esteras A., Llombart-Bosch A., Morcillo E.J.

Source: Eur Respir J 2001; 17: 1228-1235
Journal Issue: June
Disease area: Interstitial lung diseases

Congress or journal article abstractPDF journal article, handout or slidesFull text journal article

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Cortijo J., Cerda-Nicolas M., Serrano A., Bioque G., Estrela J.M., Santangelo F., Esteras A., Llombart-Bosch A., Morcillo E.J.. Attenuation by oral N-acetylcysteine of bleomycin-induced lung injury in rats. Eur Respir J 2001; 17: 1228-1235

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Oral N-acetylcysteine reduces bleomycin-induced lung damage and mucin Muc5ac expression in rats
Source: Eur Respir J 2003 Dec 01;22(6):900-905
Year: 2003



The effects of erdosteine and N-acetylcysteine treatment following lung injury on the regulation of apoptosis of capillary endothelial cells in the model of experimental pulmonary fibrosis induced by bleomycin
Source: Annual Congress 2008 - Airway cell biology and immunology
Year: 2008

The effect of pravastatin on bleomycin-induced lung injury and fibrosis in mouse
Source: Annual Congress 2010 - Determinants of acute lung injury and fibrosis
Year: 2010

Effects of edaravone, a free-radical scavenger, on bleomycin-induced lung injury in mice
Source: Eur Respir J 2008; 32: 1337-1343
Year: 2008



The effect of curcumin on bleomycin-induced pulmonary fibrosis in rats
Source: Eur Respir J 2006; 28: Suppl. 50, 827s
Year: 2006

Chronic intermittent hypoxia exacerbates lung fibrosis in bleomycin-induced lung injury mouse model
Source: International Congress 2018 – Sleep-disordered breathing: cardiovascular consequences, epidemiology, phenotypes and comorbidities
Year: 2018



Rikkunshito ameliorates bleomycin-induced lung injury in mice
Source: Annual Congress 2012 - Fibrogenesis between epithelial injury and fibroblast proliferation
Year: 2012

The effect of dexamethasone on the pulmonary fibrosis of acute lung injury induced by lipopolysaccharide in rats
Source: Annual Congress 2007 - Respiratory pathophysiology
Year: 2007


Effect of nintedanib on silica-induced lung inflammation and fibrosis in mice
Source: Annual Congress 2012 - Interstitial lung disease: from bench to bedside
Year: 2012


The effect of smoking to oxidative stress on lung tissue of rats with inhaled and intratracheal bleomycin induced pulmonary fibrosis
Source: Annual Congress 2007 - Considerations in the therapeutic approach of interstitial lung disease: oxidative stress and inflammation
Year: 2007


PD98059 attenuates the development of bleomycin-induced lung injury and fibrosis
Source: Annual Congress 2010 - Regulation of airway pharmacology
Year: 2010

Angiotensin II antagonism fails to ameliorate bleomycin-induced pulmonary fibrosis in mice
Source: Eur Respir J 2005; 25: 708-714
Year: 2005



Rho-kinase inhibitor ameliorates bleomycin-induced chronic lung injury in neonatal rats
Source: Annual Congress 2011 - Issues in paediatric and neonatal intensive care
Year: 2011

Anti-fibrotic effect of telmisartan on bleomycin-induced lung fibrosis in mice
Source: Annual Congress 2008 - Animal models of pulmonary fibrosis: mechanisms and therapies
Year: 2008

N-acetyl-L-cysteine modify prostanoids levels in bleomycin-induced lung injury
Source: Eur Respir J 2002; 20: Suppl. 38, 489s
Year: 2002

Treprostinil administration attenuates bleomycin-induced lung fibrosis in mice
Source: International Congress 2015 – Interstitial lung diseases II
Year: 2015

Effect of simvastatin on bleomycin induced pulmonary fibrosis in rats
Source: Annual Congress 2010 - Experimental approaches in pulmonary fibrosis
Year: 2010

Dexamethasone inhibits surfactant degradation during bleomycin-induced lung injury in rats
Source: Eur Respir J 2006; 28: Suppl. 50, 855s
Year: 2006

The influence of dexamethasone on the proliferation and apoptosis of pulmonary inflammatory cells in bleomycin-induced pulmonary fibrosis in rats
Source: Eur Respir J 2002; 20: Suppl. 38, 487s
Year: 2002

The rapamycin analogue SDZ RAD attenuates bleomycin-induced pulmonary fibrosis in rats
Source: Eur Respir J 2002; 19: 1124-1127
Year: 2002