TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications

Andrea Olschewski, Emma L. Veale, Bence M. Nagy, Chandran Nagaraj, Grazyna Kwapiszewska, Fabrice Antigny, Mélanie Lambert, Marc Humbert, Gábor Czirják, Péter Enyedi, Alistair Mathie

Source: Eur Respir J, 50 (5) 1700754; 10.1183/13993003.00754-2017
Journal Issue: November
Disease area: Pulmonary vascular diseases

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Andrea Olschewski, Emma L. Veale, Bence M. Nagy, Chandran Nagaraj, Grazyna Kwapiszewska, Fabrice Antigny, Mélanie Lambert, Marc Humbert, Gábor Czirják, Péter Enyedi, Alistair Mathie. TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications. Eur Respir J, 50 (5) 1700754; 10.1183/13993003.00754-2017

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Two-pore domain K+ channel TASK-1 maintains the membrane potential in non-small cell lung cancer (NSCLC) cells
Source: Annual Congress 2008 - Biology and diagnosis of thoracic tumours
Year: 2008


TRPA1 ion channel expression in human lung myofibroblasts
Source: International Congress 2019 – Translational aspects of idiopathic interstitial pneumonia
Year: 2019

Identification of a TRPM7-like non-selective cation channel in human lung mast cells
Source: Eur Respir J 2004; 24: Suppl. 48, 453s
Year: 2004

The role of amiloride sensitive epithelial sodium channel (ENaC) in cell migration of mesothelioma cells is dependent on the cell type and the extracellular matrix
Source: International Congress 2016 – Mesothelioma and malignant pleural disease
Year: 2016

The role of aquaporin-1 (AQP1) and amiloride sensitive epithelial sodium (ENaC) in cell adhesion of mesothelioma cells is cell and extracellular matrix type dependent
Source: International Congress 2015 – Malignant pleural effusions and mesothelioma
Year: 2015

Regulation and population genetics of TRP channels
Source: Research Sem. 13
Year: 2013



The chloride channel: pathology and specific therapy
Source: International Congress 2015 – Cystic fibrosis: not just for the specialists
Year: 2015



KCNK3 channel inactivation leads to pulmonary vascular alterations in rat
Source: International Congress 2018 – Pathobiology of pulmonary hypertension
Year: 2018

Stem cells, lung pathogenesis and therapeutic potential
Source: Annual Congress 2005 - Scientific year in review
Year: 2005

ENaC inhibition in cystic fibrosis: potential role in the new era of CFTR modulator therapies
Source: Eur Respir J, 56 (6) 2000946; 10.1183/13993003.00946-2020
Year: 2020



Genetic alteration in the mammalian chloride channel CLNS1A alter lung function in children
Source: Eur Respir J 2006; 28: Suppl. 50, 476s
Year: 2006

The cystic fibrosis transmembrane conductance regulator and its modulators: clinical implications
Source: Virtual Congress 2020 – Respiratory infections
Year: 2020


KCa3.1 ion channel is expressed by component cells of lymphangioleiomyomatosis (LAM) nodules
Source: International Congress 2019 – Innovative approaches for management and treatment of rare diffuse parenchymal lung diseases
Year: 2019


The pathophysiological roles of a voltage-gated potassium channel Kv1.5 in toluene diisocyanate-induced asthma
Source: Eur Respir J 2002; 20: Suppl. 38, 29s
Year: 2002

The emerging role of transient receptor potential channels in chronic lung disease
Source: Eur Respir J, 50 (2) 1601357; 10.1183/13993003.01357-2016
Year: 2017



Ion channel modulation by adenosine in human lung mast cells
Source: Eur Respir J 2005; 26: Suppl. 49, 225s
Year: 2005

Inhibition of Ca2+-release activated Ca2+ channel (CRAC) and K+ channels of Jurkat T cell by curcumin
Source: Annual Congress 2010 - Mechanisms and modulation of allergic inflammation in the lung
Year: 2010