Reprogramming of cellular metabolism: driver for airway remodelling in COPD?

Pieter S. Hiemstra, Anne M. van der Does

Source: Eur Respir J, 50 (5) 1702197; 10.1183/13993003.02197-2017
Journal Issue: November
Disease area: Airway diseases

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Pieter S. Hiemstra, Anne M. van der Does. Reprogramming of cellular metabolism: driver for airway remodelling in COPD?. Eur Respir J, 50 (5) 1702197; 10.1183/13993003.02197-2017

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
The GPx1-PTP1B-PP2A axis: A key determinant of airway inflammation and alveolar destruction
Source: Annual Congress 2013 –Acute lung injury: novel clinical and experimental insights
Year: 2013


Targeting ASK1 in preventing airway smooth muscle growth: Implications for airway remodeling in COPD
Source: International Congress 2016 – New findings in mucosal immunology
Year: 2016


The role of altered stem cell function in airway and alveolar repair and remodelling in COPD
Source: Eur Respir Monogr 2021; 91: 322-339
Year: 2021


IL-17A is elevated in patients with COPD and contributes to airway remodeling by acting on fibroblasts
Source: International Congress 2016 – What's new in biomarker analysis?
Year: 2016

Altered airway epithelial cell specification in COPD
Source: International Congress 2015 – Translational studies in airway cell biology
Year: 2015


Inflammatory cell microlocalisation and airway dysfunction: cause and effect?
Source: Eur Respir J 2007; 30: 1043-1056
Year: 2007



A role for WNT-5B in airway remodeling in COPD by activation of TGF-beta/Smad3 signaling?
Source: Annual Congress 2013 –COPD: experimental biology
Year: 2013

Inflammatory cells and airway remodelling in COPD: clinical implications
Source: International Congress 2019 – It takes two to tango: translating scientific findings into clinical applications
Year: 2019


Lung ageing and COPD: is there a role for ageing in abnormal tissue repair?
Source: Eur Respir Rev, 26 (146) 170073; 10.1183/16000617.0073-2017
Year: 2017



Are asthma and COPD translation control diseases? Translational defect of cell cycle regulators C/EBP-α and -δ in airway smooth muscle cells (ASMC) of patients with asthma and COPD
Source: Eur Respir J 2005; 26: Suppl. 49, 20s
Year: 2005

The role of circulating mitochondrial DNA in modulating airway inflammation of chronic obstructive pulmonary disease
Source: International Congress 2014 – Cell biology 2014
Year: 2014

Expression of vascular remodeling markers in relation to bradykinin receptors in asthma and COPD
Source: Annual Congress 2013 –Emerging new targets for the treatment of respiratory diseases
Year: 2013


Altered iron metabolism and elevated cellular senescence in COPD small airway epithelial cells
Source: Virtual Congress 2020 – Metabolic alterations and ageing in lung disease
Year: 2020




Myofibroblast expression in airways and alveoli is affected by smoking and COPD
Source: Annual Congress 2013 –COPD: new markers of diseases
Year: 2013

Inflammatory cells and airway remodelling in COPD
Source: International Congress 2019 – It takes two to tango: translating scientific findings into clinical applications
Year: 2019


Defective metabolic adaptation in the pathogenesis of COPD
Source: International Congress 2019 – Metabolic alterations as a driver of chronicity in lung disease
Year: 2019


Investigating mitochondrial dysfunction in asthma
Source: International Congress 2015 – Advances in the future treatment of severe asthma
Year: 2015


MicroRNA-34a drives small airway fibroblast cellular senescence in COPD
Source: International Congress 2017 – New Mechanistic Findings in COPD
Year: 2017



Essential roles of q110 in IL13 in airway remodelling in bronchial asthma
Source: Annual Congress 2009 - Airways remodelling
Year: 2009



Reduced MicroRNA-19a causes constitutive high expression of PRMT1 and remodeling in asthma
Source: International Congress 2016 – New therapies and therapeutic targets
Year: 2016