Central role for phosphoinositide-3-kinase gamma/delta dependent signalling in eosinophilic pulmonary inflammation driven by innate lymphoid cells

M. Thomas (Gothenburg, Sweden)

Source: International Congress 2017 – Therapeutic approaches in lung disease
Session: Therapeutic approaches in lung disease
Session type: Poster Discussion
Number: 4920
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Thomas (Gothenburg, Sweden). Central role for phosphoinositide-3-kinase gamma/delta dependent signalling in eosinophilic pulmonary inflammation driven by innate lymphoid cells. 4920

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Profibrotic function of pulmonary group 2 innate lymphoid cells is controlled by regnase-1
Source: Eur Respir J, 57 (3) 2000018; 10.1183/13993003.00018-2020
Year: 2021



NTHi-induced inflammation activates the PD-1 immune checkpoint in the tumor microenvironment
Source: International Congress 2018 – Lung cancer: novel molecular markers and mechanisms
Year: 2018



The role of innate immune cells in inflammation
Source: International Congress 2015 – Resolving inflammation
Year: 2015



Allergen-experienced group 2 innate lymphoid cells acquire memory-like properties and enhance allergic lung inflammation
Source: International Congress 2018 – Roles of innate lymphoid cells in asthma
Year: 2018


γδ T cells contribute to local and systemic B cell reactivity in allergic eosinophilic airway inflammation but without a major influence on the TH1/TH2 balance
Source: Eur Respir J 2002; 20: Suppl. 38, 568s
Year: 2002

Over-expression of SIGIRR attenuates TLR 4,5,9-mediated immune responses in human airway epithelial cells
Source: Annual Congress 2009 - Mechanisms of infection: what's new?
Year: 2009

Role of innate lymphoid cells and the epithelium in asthma and bronchoconstriction
Source: International Congress 2018 – It's my favourite cell that affects your asthma
Year: 2018


The innate immune response to rhinovirus in bronchial epithelial cells is predominately controlled by signalling initiated via MDA-5
Source: Annual Congress 2010 - Mechanisms of asthma and lung inflammation
Year: 2010


The role of innate lymphoid cells (ILCs) in a murine model of irritant-induced asthma.
Source: Virtual Congress 2020 – New insight into the immunology of asthma and COPD
Year: 2020


NFAT subtypes in regulating Th2 lymphocytes
Source: Annual Congress 2012 - COPD treatments: efficacy and safety
Year: 2012

CD6 is expressed on human airway and blood innate lymphoid cells (ILCs) and is upregulated by epithelial alarmins IL-33 and TSLP
Source: Virtual Congress 2020 – Novel molecular markers and targets for asthma phenotypes
Year: 2020


The innate immune function of airway epithelial cells in inflammatory lung disease
Source: Eur Respir J 2015; 45: 1150-1162
Year: 2015



A pathogen-activated innate homing pathway that instructs allergic inflammation
Source: Annual Congress 2007 - Regulation of allergic airway inflammation in animal models of asthma
Year: 2007


The immunomodulator, FTY720, leads to sequestration of T cells in the bronchial associated lymphoid tissue (BALT) and inhibits allergen-induced airway remodeling
Source: Annual Congress 2010 - Asthma: basic science and clinical studies
Year: 2010

Human CD40 ligand-expressing type 3 innate lymphoid cells induce interleukin (IL)-10-producing immature transitional regulatory B-cells
Source: International Congress 2018 – Roles of innate lymphoid cells in asthma
Year: 2018


Dysregulation of type 2 innate lymphoid cells and Th2 cells impairs pollutant-induced allergic airway responses
Source: International Congress 2016 – Immune responses in the lung
Year: 2016

Innate lymphoid cells as new players in tissue homeostasis and inflammation
Source: International Congress 2014 – Innate lymphoid cells in lung immunology and diseases
Year: 2014

Nlrc5 is involved in allergic airway inflammation and negatively regulates inflammatory signaling pathway via TLR2/NF-?B.
Source: International Congress 2018 – Translational models of the immunopathology that underlies airway obstructive diseases
Year: 2018

Airway epithelial cells activate anti-viral pathways in human dendritic cells
Source: Annual Congress 2009 - Lung cell biology and immunology
Year: 2009