LSC - 2017 - A critical role for mTOR regulated metabolic reprogramming during TGF-ß induced fibroblast collagen synthesis Source: International Congress 2017 – Novel mechanisms and therapeutic targets in lung injury and repair Year: 2017
A critical role for mTOR regulated metabolic reprogramming during TGF-? induced fibroblast collagen synthesis Source: ERS Lung Science Conference 2017 Year: 2017
LSC - 2018 - FKBP10 regulates fibroblast migration via synthesis of collagen VI Source: International Congress 2018 – New insights in the signalling pathways that underlie IPF pathophysiology Year: 2018
In vitro profibrotic effects of rapamycin on basal or TGF-β1 induced primary human lung fibroblast: ECM production and turnover, migration and differentiation Source: Annual Congress 2012 - Diffuse parenchymal lung disease I Year: 2012
Differential role of EPAC and PKA in the transduction of cAMP-mediated inhibition of human lung fibroblast proliferation and collagen synthesis Source: Annual Congress 2009 - Pathological remodelling in chronic lung disease: from epithelial-mesenchymal transition to cellular activation Year: 2009
LSC - 2018 - MTOR regulates TGFß-induced collagen synthesis via increased glycine biosynthesis Source: International Congress 2018 – Pulmonary fibrosis: from models to patients Year: 2018
LSC - 2018 - PRRX1 a pro-fibrotic mesenchymal transcription factor modulated by remodeled microenvironment in IPF Source: International Congress 2018 – New insights in the signalling pathways that underlie IPF pathophysiology Year: 2018
Epigenetic deregulated translation control of C/EBP-alpha leads to increased mesothelioma cell proliferation Source: Annual Congress 2011 - Pleural and mediastinal malignancies: management and rare clinical cases Year: 2011
TGFβ induced myofibroblast differentiation is independent of p38 activation, but requires TGFβR1 kinase activity and correlates with TGFβ-mediated SMAD signaling and TGFβ-responsive gene expression patterns in human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 718s Year: 2004
Notch activity is required for myofibroblast differentiation Source: International Congress 2019 – Oxidative stress, hypoxia and microbial exposure in the pathogenesis of pulmonary disease Year: 2019
The long non-coding MALAT-1 stimulates cellular growth, migration and proliferation Source: Annual Congress 2012 - New aspects of lung cancer biology Year: 2012
VEGF induces ECM synthesis and fibroblast activity in human lung fibroblasts Source: International Congress 2017 – Towards better treatments for lung disease: experimental pharmacology Year: 2017
Decreased expression of FENDRR, a lung mesenchymal long non-coding RNA, regulates fibroblast phenotypes in IPF through NOX4. Source: International Congress 2017 – Functional genomics knowledge in parenchymal and bronchial diseases Year: 2017
Role of phosphatidylinositol-3-kinase (PI3K) in TGF-β-induced proliferation and differentiation of human lung fibroblasts into myofibroblasts Source: Annual Congress 2011 - Genetic and molecular background in pulmonary fibrosis Year: 2011
Effects of TGF-beta and budesonide on MAPK phosphorylation, IL-6/IL-11 secretion, and cell proliferation in human lung fibroblasts Source: Eur Respir J 2006; 28: Suppl. 50, 662s Year: 2006
Roles of Rho-Rock and Smad pathways in TGFβ1-mediated lung fibroblast differentiation Source: Annual Congress 2008 - Regulatory mechanisms of cell activation, renewal and recruitment Year: 2008
FKBP10 regulates fibroblast migration via synthesis of collagen VI Source: ERS Lung Science Conference 2018 Year: 2018
TGF-beta-induced transgelin 1 expression contributes to epithelial-to-mesenchymal transition in lung fibrosis Source: Eur Respir J 2006; 28: Suppl. 50, 604s Year: 2006
LSC - 2017 - RNA-Seq analysis reveals major differences between the effects of rapamycin and dual mTORC1/2 inhibition during TGFß1-induced myofibroblast differentiation Source: International Congress 2017 – Cellular signalling pathways in pulmonary fibrosis Year: 2017