Heterozygous genotype rs17580 AT (PiS) in SERPINA1 is associated to COPD secondary to biomass and tobacco smoke.

R. Falfán Valencia (Mexico, Mexico)

Source: International Congress 2017 – Current molecular and genetic understanding of lung diseases
Session: Current molecular and genetic understanding of lung diseases
Session type: Thematic Poster
Number: 962
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
R. Falfán Valencia (Mexico, Mexico). Heterozygous genotype rs17580 AT (PiS) in SERPINA1 is associated to COPD secondary to biomass and tobacco smoke.. 962

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
TNF promoter polymorphisms are associated with susceptibility and increased severity in secondary to tobacco and biomass smoke COPD in Mexican population
Source: International Congress 2015 – Promising novel findings in translational pulmonary research
Year: 2015

The role of genetic polymorphisms of glutation-S-transferase μ1 (GSTM1) and gelatinase B (MMP9) in the risk of COPD development
Source: Annual Congress 2003 - Alpha-1 antitrypsin deficiency and COPD
Year: 2003


Glutathion-S-Transferase M1 (GSTM1) genotype plus prenatal exposure to tobacco smoke as risk factors for pediatric asthma
Source: Eur Respir J 2005; 26: Suppl. 49, 451s
Year: 2005

High frequency of CFTR R75Q variant and mEPHX „slow" allele in COPD patients
Source: Eur Respir J 2005; 26: Suppl. 49, 343s
Year: 2005

Are ADAM33, TNF, LTA, EPHX1 and ADRB2 polymorphisms (SNPs) associated with COPD in a large case-control study when cases and controls are purified?
Source: Eur Respir J 2007; 30: Suppl. 51, 131s
Year: 2007

Replication association study IREB2, CHRNA5, CHRNA3, CHRNB4, FAM13A, HTR4, and HHIP genes polymorphisms with chronic obstructive pulmonary disease in Tatar population from Russia
Source: International Congress 2016 – Role of genetics and exposures in COPD and asthma
Year: 2016


M2 allele of alpha1-antitrypsin gene and genetic susceptibility to COPD in Korean men
Source: Eur Respir J 2005; 26: Suppl. 49, 442s
Year: 2005

Exposure to environmental tobacco smoke in childhood and GSTM1 polymorphism are associated to lung function in adults
Source: Annual Congress 2008 - Epidemiology of asthma and allergy
Year: 2008

Genetic variants in NRXN1, CHRNA3, CHRNA5 and CHRNB4 are associated with smoking and increased consumption of cigarettes per day in a Mexican mestizo population
Source: International Congress 2015 – Genetics and environmental factors in phenotypes of asthma and COPD
Year: 2015

Genetic association between COPD and polymorphisms in TNF, ADRB2 and EPHX1
Source: Eur Respir J 2006; 27: 682-688
Year: 2006



No association between COPD and ADAM33, TNF, EPHX1 and ADRB2 polymorphisms (SNPs) in a large case-control study
Source: Eur Respir J 2006; 28: Suppl. 50, 584s
Year: 2006

Impact of -1562 C/T polymorphism of MMP9 gene on COPD susceptibility in Polish patients.
Source: International Congress 2014 – Genetics and environmental factors underlying asthma and COPD
Year: 2014

Metabolic gene polymorphisms (CYP1A1, EPHX1, GSTM1 and GSTP1) associations with the severity of cystic fibfosis airway disease
Source: Eur Respir J 2003; 22: Suppl. 45, 173s
Year: 2003

Influence of allele variants of CYP2A6 and NAT2 genes on features of phenotype of tobacco smoker
Source: Eur Respir J 2004; 24: Suppl. 48, 503s
Year: 2004

GSTT1 null alleles are risk factors for excess FEV1 decline in the general population, but GSTM1 null alleles only in smokers
Source: Eur Respir J 2007; 30: Suppl. 51, 447s
Year: 2007

TNF-α (-308A) allele carriage is associated with OSAHS
Source: Annual Congress 2003 - Systematic inflammation and metabolic disorders in sleep related breathing disorders
Year: 2003


Genes, the environment and the lung
Source: Annual Congress 2006 - Genes, environment and the lung
Year: 2006


Limitation of cigarette consumption by CYP2A6*4, *7 and *9 polymorphisms
Source: Eur Respir J 2006; 27: 289-292
Year: 2006



Novel genetic variants in alpha-1 antitripsin deficiency cases carrying S alleles and discordant genotype and serum levels
Source: International Congress 2015 – Promising novel findings in translational pulmonary research
Year: 2015

Detoxifying enzymes genes (EPHX1, CYP1A1 and GSTP1) genotypes and risk of chronic obstructive pulmonary disease
Source: Eur Respir J 2003; 22: Suppl. 45, 196s
Year: 2003