A phenotypic high-throughput screening assay for the pharmacological inhibition of the pathological deposition of extracellular matrix Source: ERS Lung Science Conference 2018 Year: 2018
Clinically validated markers of the extracellular matrix remodelling are altered by potential anti-fibrotic compounds in a human lung fibrosis ex vivo model Source: International Congress 2018 – Preclinical pharmacology: novel targets in airway inflammation, narrowing and neural control Year: 2018
RNAscope in situ hybridization allows spatial estimation of free drug exposure through quantification of drug induced gene expression Source: International Congress 2019 – COPD clinical studies: bronchodilators, corticosteroids and more Year: 2019
In vivo pharmacological profile of PKF242-484 and PKF241-466, novel dual inhibitors of TNF-α converting enzyme and matrix metalloproteinases, in models of airway inflammation Source: Eur Respir J 2002; 20: Suppl. 38, 169s Year: 2002
Modern molecular direct tests for rapid identification and drug susceptibility testing of Mycobacterium tuberculosis Source: Annual Congress 2012 - Microbiological advances in the diagnosis of tuberculosis Year: 2012
Comparison of drug delivery from spacers using a standard in vitro and an ex vivo method Source: Annual Congress 2008 - Recent advances in the treatment and pathogenesis of asthma Year: 2008
Comparative mycobacterial genomics as a tool for drug target and antigen discovery Source: Eur Respir J 2002; 20: 78S-86S Year: 2002
Time-resolved proteomic characterization of ECM remodelling in human lung scaffold cultures using stable isotope labelling Source: ERS Lung Science Conference 2018 Year: 2018
Patient derived lung tissue cultures for drug identification and validation Source: International Congress 2017 – Innovative approaches to model human lung diseases Year: 2017
Development of in vitro assays to predict fibrogenesis and replace animal testing Source: Eur Respir J 2006; 28: Suppl. 50, 521s Year: 2006
Proteomics of serum extracellular vesicles identifies a novel COPD biomarker, fibulin-3 from elastic fibres Source: ERJ Open Res, 7 (1) 00658-2020; 10.1183/23120541.00658-2020 Year: 2021
T-cell biomarkers for diagnosis of tuberculosis: candidate evaluation by a simple whole blood assay for clinical translation Source: Eur Respir J, 51 (3) 1800153; 10.1183/13993003.00153-2018 Year: 2018
Gene expression profiling: identifying novel gene targets for therapeutic intervention Source: Annual Congress 2008 - PG8 - Cellular and molecular technologies of today - treatments of tomorrow Year: 2008
Genetic studies as a tool for identifying novel potential targets for treatment of COPD Source: Eur Respir J, 50 (5) 1702042; 10.1183/13993003.02042-2017 Year: 2017
Genomics-based identification of targets in pathogenic bacteria for potential therapeutic use Source: Annual Congress 2004 - Novel approaches to the treatment of pneumonia Year: 2004
SFTA3, a novel protein of the lung: three-dimensional structure, characterisation and immune activation Source: Eur Respir J 2014; 44: 447-456 Year: 2014