Adoptive transfer of T-helper cell type 1 clones attenuates an asthmatic phenotype in mice

Irifune K., Yokoyama A., Sakai K., Watanabe A., Katayama H., Ohnishi H., Hamada H., Nakajima M., Kohno N., Higaki J.

Source: Eur Respir J 2005; 25: 653-659
Journal Issue: April
Disease area: Airway diseases

Congress or journal article abstractPDF journal article, handout or slidesFull text journal article

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Irifune K., Yokoyama A., Sakai K., Watanabe A., Katayama H., Ohnishi H., Hamada H., Nakajima M., Kohno N., Higaki J.. Adoptive transfer of T-helper cell type 1 clones attenuates an asthmatic phenotype in mice. Eur Respir J 2005; 25: 653-659

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Macrophages induce an allergen-specific and long-term suppression in a mouse asthma model
Source: Eur Respir J 2005; 26: 1040-1046
Year: 2005



Cytokine production of RSV/PHA-stimulated tonsillar mononuclear cells: influences of age and atopy
Source: Eur Respir J 2003; 22: 317-322
Year: 2003



T-helper 1 cells induce alveolitis but do not lead to pulmonary fibrosis in mice
Source: Eur Respir J 2003; 21: 11-18
Year: 2003



T-helper cell type-2 regulation in allergic disease
Source: Eur Respir J 2005; 26: 1119-1137
Year: 2005



CD4 + T-helper cells engineered to produce IL-10 reverse allergen-induced airway hyperreactivity and inflammation
Source: Eur Respir J 2001; 18: Suppl. 33, 432s
Year: 2001

Pathophysiology of asthma
Source: ISSN=1025-448x, ISBN=1-904097-26-x, page=84
Year: 2003

Increase of both blood CXCR3+ and CCR4+ helper T cells associated with severity of asthma
Source: Annual Congress 2005 - Inflammation and remodelling in allergy and asthma
Year: 2005


Different Th1, Th2, Th17 and Treg associated chemokine local pattern expression in lung in a murine model of allergic inflammation
Source: Annual Congress 2011 - T-cell subsets
Year: 2011


Interferon-γ-pretreated dendritic cells induced dual Th1 and Th2 responses and failed to prevent development of allergic airway inflammation
Source: Eur Respir J 2006; 28: Suppl. 50, 230s
Year: 2006

Modified mRNA encoding Foxp3 protects against allergic asthma in mice by rebalancing T helper cell responses through an IL-23 / IL-17A-dependent mechanism
Source: Annual Congress 2012 - Treating childhood asthma
Year: 2012

Dendritic cell subsets in the lung: implication for allergic asthma
Source: Annual Congress 2006 - A new look at dendritic cell interactions in the lung
Year: 2006


Fevipiprant is superior to montelukast in suppressing type 2 cytokine production from mast cell stimulated human Th2 cells
Source: International Congress 2019 – Precision meets immunology in treatment of airway diseases
Year: 2019




Low number of regulatory T cells in bronchial asthma: association with inflammatory cytokines
Source: Annual Congress 2009 - Infections, immunity and inflammation
Year: 2009



ILC2 cells from severe allergic and eosinophilic asthma demonstrate increased expression of TSLP receptor (TSLPR) and enhanced proliferative capacity.
Source: Virtual Congress 2021 – New insight into the immunology of allergies, asthma and COPD: from mouse to man
Year: 2021


Enhanced expression of IL-18 and increased CD8+ T cells and eosinophils in the airways of asthma death
Source: Annual Congress 2010 - Mechanisms of asthma and lung inflammation
Year: 2010


T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED
Source: Eur Respir J , 49 (2) 1602135; DOI: 10.1183/13993003.02135-2016
Year: 2017



Effects of depletion of CD4+CD25+ T cells with anti-CD25McAb on airway inflammation of asthmatic mice
Source: Eur Respir J 2005; 26: Suppl. 49, 24s
Year: 2005

Regulatory role of antigen-induced IL-10, produced by Tr1 cells, in airway neutrophilia in a murine model for asthma
Source: Annual Congress 2012 - Asthma: mechanisms of airway inflammation
Year: 2012


γδ T cells contribute to local and systemic B cell reactivity in allergic eosinophilic airway inflammation but without a major influence on the TH1/TH2 balance
Source: Eur Respir J 2002; 20: Suppl. 38, 568s
Year: 2002