Source: Annual Congress 2001 - Cardiovascular pathophysiology in OSA
Disease area: Pulmonary vascular diseases, Sleep and breathing disorders

Abstract

A new sensor was recently introduced which reflects peripheral circulatory responses to disordered breathing. This peripheral arterial tonometry (PAT) sensor selectively measures the arterial component of finger volume changes accompanying the pulse wave. These changes are an integral part of the hemodynamic response to obstructive sleep apnea related arousal. In order to directly relate these changes to hemodynamic changes we compared PAT and invasive blood pressure.
20 patients with obstructive sleep apnea (AHI>20) and arterial hypertension were recorded with polysomnography blood pressure and the PAT signal. Attenuations in the amplitude of PAT signal by 50% were counted.
Attenuations in the PAT signal were related to apneas, oxygen desaturations and arousals. Invasive blood pressure swings reflected apnea and hypopnea events. The PAT signal did follow apnea related blood pressure changes in a complex way. The initial decrease in blood pressure at the beginning of an apnea is accompanied by an increase in the PAT signal. The increase of blood pressure is accompanied by a distinct drop in the PAT signal. Correlations with apneas and arousals were significant.
The PAT signal is a good marker for arousal with concomitant cardiovascular changes. The direct comparison with blood pressure indicates that the PAT signal reflects changes in sympathetic tone and stroke volume. Local vascular tone changes also influence the signal, so a direct relation between PAT and stroke volume cannot be expected.

Rating:

Share or cite this content

Citations should be made in the following way:
T. Penzel, R. Fricke, H. F. Becker, A. Jerrentrup, J. H. Peter (Marburg, Germany). Comparison of peripheral arterial tonometry and invasive blood pressure in patients with obstructive sleep apnoea. Eur Respir J 2001; 16: Suppl. 31, 3499

Member's Comments

No comment yet.

Related content which might interest you: Peripherial arterial tonometry versus polysomnography in suspected obstructive sleep apnea Source: Virtual Congress 2020 – Phenotyping sleep-disordered breathing and its impact on various diseases Year: 2020 Influence of continuous positive airway pressure therapy on endothelial function and blood pressure in patients with arterial hypertension and obstructive sleep apnoea syndrome Source: Eur Respir J 2006; 28: Suppl. 50, 814s Year: 2006 Regional cerebral blood flow in patients with obstructive sleep apnoea syndrome after continuous positive airway pressure therapy Source: Annual Congress 2009 - Assessment and therapeutical interventions in obstructive sleep apnoea Year: 2009 Management of hypertension in obstructive sleep apnoea: predicting blood pressure reduction under continuous positive airway pressure Source: Eur Respir J, 50 (4) 1701822; 10.1183/13993003.01822-2017 Year: 2017 Automated office blood pressure measurement increases prevalence of masked hypertension in patients with obstructive sleep apnoea Source: Virtual Congress 2020 – Consequences for obstructive sleep apnoea and potential modalities for early identification Year: 2020 The relationship between hypoxemia and ambulatory blood pressure in obstructive sleep apnea-hypopnea syndrome Source: Eur Respir J 2007; 30: Suppl. 51, 592s Year: 2007 Blood pressure responsiveness to obstructive events during sleep after chronic CPAP Source: Eur Respir J 2003; 21: 509-514 Year: 2003 Falls in blood pressure in patients with obstructive sleep apnea syndrome after long-term nasal continuous positive airway pressure treatment Source: Eur Respir J 2005; 26: Suppl. 49, 38s Year: 2005 Continuous positive airway pressure does not reduce blood pressure in nonsleepy hypertensive OSA patients Source: Eur Respir J 2006; 27: 1229-1235 Year: 2006 Effects of treatments with nCPAP on cerebral blood flow velocity in patients with obstructive sleep apnea syndrome (OSAS) Source: Annual Congress 2009 - Assessment and therapeutical interventions in obstructive sleep apnoea Year: 2009 Effects of continuous positive airway pressure therapy in patients with severe obstructive sleep apnea and endothelial dysfunction on 24-hour blood pressure profile Source: International Congress 2015 – Inflammation, biomarkers and hypoxia in sleep disordered breathing Year: 2015 Non-dipping nocturnal blood pressure correlates with obstructive sleep apnoea severity in normotensive subjects and may reverse with therapy Source: ERJ Open Res, 7 (3) 00338-2021; 10.1183/23120541.00338-2021 Year: 2021 Differential blood pressure response to continuous positive airway pressure treatment according to the circadian pattern in hypertensive patients with obstructive sleep apnoea Source: Eur Respir J, 54 (1) 1900098; 10.1183/13993003.00098-2019 Year: 2019 Effects of autoCPAP treatment for obstructive sleep apnea on 24-hour blood pressure and nocturnal catecholamines Source: Annual Congress 2009 - Continuous positive airway pressure therapy in obstructive sleep apnoea Year: 2009 Importance of controlled blood pressure values in a population with obstructive sleep apnea syndrome (OSA) and arterial hypertension (HT) Source: Annual Congress 2011 - Cardiometabolic and neurocognitive changes in obstructive sleep apnoea Year: 2011 Blood pressure reactivity to obstructive apnoeas before and after long-term CPAP Source: Eur Respir J 2001; 18: Suppl. 33, 519s Year: 2001 Blood pressure response to CPAP treatment in subjects with obstructive sleep apnoea: the predictive value of 24-h ambulatory blood pressure monitoring Source: Eur Respir J, 50 (4) 1700651; 10.1183/13993003.00651-2017 Year: 2017 A comparison of peripheral arterial tone technology with limited polygraphy to diagnose obstructive sleep apnoea in UK Source: International Congress 2017 – Diagnostic approaches to obstructive sleep apnoea Year: 2017 Correlations between severity of obstructive sleep apnoea and systolic pulmonary artery pressure: preliminary results Source: International Congress 2018 – Cardiovascular and metabolic consequences of sleep-disordered breathing Year: 2018 Decrease in blood pressure during continuous positive airway pressure treatment for obstructive sleep apnoea: still searching for predictive factors Source: Eur Respir J, 54 (1) 1901219; 10.1183/13993003.01219-2019 Year: 2019