Source: Annual Congress 2001 - Drug resistant TB
Disease area: Respiratory infections

Abstract

1928 cases of drug resistant tuberculosis were confirmed by the method of culture of the sputum at Kaunas Romainiai tuberculosis hospital during the period of 1997 - 1999. 560 of them were diagnosed for the first time (not treated or treated for less than 1 month). 1362 of confirmed cases were the "old ones" (treatment failures, relapses, treated with one or two courses of antimicrobial therapy). The resistance to H, R, E, S and multidrug resistance have been investigated. We have revealed that among the "new" cases of tuberculosis the resistance of M. tuberculosis has decreased. In 1997 the resistance to H was 27.5 percent. However, it decreased to 24.8 percent in 1998 and to 7.6 percent in 1999. In 1997 the resistance to R was 19.9 percent and it has decreased to 9.0 percent and 1.9 percent in 1998 and 1999, respectively. In 1997 the resistance to E was 1.1 percent. It has reached 1.5 percent in 1998 and there was no resistance to E in 1999. In 1997 the resistance to S was 15.6 percent. In 1998 it was 18.7 percent and droped to 3.1 percent in 1999. Thus, we have revealed the statistically significant decrease in resistance to H, R and S. This phenomen could be explained by successfull introduction of Directly Observed Treatment Strategy (DOTS).

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Citations should be made in the following way:
A. Naudziunas, A. Andriuskeviciene (Kaunas, Lithuania). Drug-resistant tuberculosis in Lithuania (Kaunas region). Eur Respir J 2001; 16: Suppl. 31, 3467

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