Source: Annual Congress 2001 - Drug resistant TB
Disease area: Respiratory infections

Abstract

The aim of the study was to investigate and to compare the rate of Multiple drug resistant tuberculosis (MDRTB) in Varna and Plovdiv regions (Bulgaria) during the period 1993-1999. All patients with drug-susceptibility testing (DST) treated for tuberculosis were included. They were divided in two groups-group A-291 patients in Varna region and group B-494 patients in Plovdiv region. Lovenstein-Jensen medium was used for mycobacterial isolation. Drug resistance to Rifampicin (R) and Isoniazid (H), Streptomycin and Ethambutol was tested. MDRTB was defined as resistance to at least R and H. The mean percentages of combined MDRTB were 7,9% and 4,6% respectively. The highest percentages were registered in 1993-18,4% in Varna region and 11,3% in Plovdiv region. The curves of multiple drug resistance in both regions showed a second peak in 1998 with 8,3% and 6,1% respectively.
Conclusions: a high rate of MDRTB was registered in Plovdiv and Varna regions during the period 1993-1999 and the mean percentage of combined multiple drug resistance was higher in Varna region. The highest percentage in both regions was registered in 1993 with a second peak in 1998.

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Citations should be made in the following way:
S. Levterova, A. Torossian, Z. Tankova (Varna, Plovdiv). Multiple drug-resistant tuberculosis in Varna and Plovdiv regions (Bulgaria), 1993-1999. Eur Respir J 2001; 16: Suppl. 31, 3462

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