Involvement of 5-lipoxygenase (5-LO) pathway in eosinophil chemotaxis to acetylsalicylic acid (ASA) in aspirin-sensitive and healthy non-allergic subjects Source: Eur Respir J 2002; 20: Suppl. 38, 382s Year: 2002
Sulfidoleukotrienes (sLT) production in vitro by blood leucocytes in asthmatic patients treated with theophylline (T) Source: Eur Respir J 2001; 18: Suppl. 33, 263s Year: 2001
15-LOXb is the enzymatic source of aspirin induced 15-HETE generation in aspirin-sensitive patients Source: Eur Respir J 2005; 26: Suppl. 49, 342s Year: 2005
Quantitative assessment of cysteinyl leukotrienes in human sputum during the allergen-induced asthmatic response and the effect of GSK2190915, a 5-lipoxygenase activating protein (FLAP) inhibitor Source: Annual Congress 2011 - Diagnosis and treatment of inflammatory respiratory diseases Year: 2011
Inhalation of mannitol, used as a model for exercise-induced bronchoconstriction (EIB), causes release of leukotrienes and a mast cell marker in asthmatic subjects Source: Eur Respir J 2001; 18: Suppl. 33, 102s Year: 2001
The influence of antileukotriene therapy with montelukast (M) on thromboxane B2 /leukotriene E4 (TXB2 /LTE4 ) ratio in the urine of asthmatic subjects and other inflammatory markers Source: Eur Respir J 2003; 22: Suppl. 45, 102s Year: 2003
Assessment of in vivo 5-lipoxygenase (5-LO) activity in nonatopic and atopic subjects with or without asthma: effects of treatment with the 5-LO inhibitor zileuton Source: Eur Respir J 2003; 22: Suppl. 45, 101s Year: 2003
Steroid-induced BAL lymphocyte (L-BAL) apoptosis as prognostic factor in patients with bronchial asthma (AB) Source: Eur Respir J 2005; 26: Suppl. 49, 281s Year: 2005
Eicosanoid concentrations in induced sputum (IS) in stable asthmatics with aspirin-tolerant (ATA) and aspirin-intolerant asthma (AIA) Source: Eur Respir J 2005; 26: Suppl. 49, 575s Year: 2005
Low doses of inhaled fluticasone propionate induce sputum eosinophil apoptosis and inhibit IL-5 release in naive symptomatic asthmatics (FLIC19) Source: Eur Respir J 2001; 18: Suppl. 33, 336s Year: 2001
Inhibitors of PDE4 delay eosinophil apoptosis Source: Annual Congress 2005 - Improving asthma control in the harder-to-reach population Year: 2005
Inhibition of the asthmatic allergen challenge response by the CRTH2 antagonist OC000459 Source: Eur Respir J 2013; 41: 46-52 Year: 2013
The eosinophil is important in asthma after all – Con Source: Annual Congress 2006 - Pro/Con: asthma is (not) an inflammatory disease Year: 2006
Imbalance of anti-inflammatory (resolving D1) and pro-inflammatory (leukotrien B4) arachidonic acid products in exhaled breath condensate of severe refractory asthma. Source: International Congress 2017 – Airway disease and exacerbations Year: 2017
A leukotriene antagonist, montelukast, reduces in vitro LTD4 increases in peripheral blood eosinophil progenitor colonies in atopic subjects Source: Eur Respir J 2001; 18: Suppl. 33, 531s Year: 2001
The effect of a leukotriene antagonist, pranlukast, on allergen-induced airway responses and circulating dendritic cells in subjects with atopic asthma Source: Eur Respir J 2003; 22: Suppl. 45, 414s Year: 2003
PUR1800 (RV1162), A novel narrow spectrum kinase inhibitor, but not Fluticasone, reduces TNFa-induced cytokine release by primary bronchial epithelial cells from healthy volunteers and COPD patients Source: International Congress 2018 – Preclinical pharmacology: novel targets in airway inflammation, narrowing and neural control Year: 2018
Serum‘s factors inhibit erythropoiesis in patients with non-atopic asthma (NAA) Source: Eur Respir J 2004; 24: Suppl. 48, 352s Year: 2004
Possible anti-inflammatory effect of salmeterol against interleukin-8 and neutrophil activation in asthma in vivo Source: Eur Respir J 2003; 21: 994-999 Year: 2003
The effect of GSK2190915, a 5-lipoxygenase activating protein inhibitor, on the early asthmatic response to inhaled allergen Source: Annual Congress 2011 - Asthma management and response Year: 2011