Lung function in postmenopausal women from the UK Biobank

Andre Amaral (London, United Kingdom), Andre Amaral, David Strachan, Francisco Gomez Real, Peter Burney, Deborah Jarvis

Source: International Congress 2016 – Important factors, besides smoking, that relate to lung function and decline in lung function
Disease area: Airway diseases

Congress or journal article abstract

Abstract

It is recognized that housing conditions like dampness and mould can contribute to respiratory symptoms and disease due to microbial agents. Studies have shown increase in symptoms and decline in lung function associated with damp and mould at home (Tischer C, et al. BMC Pulm Med (2015) 15:48. Aim: To study the association between respiratory symptoms and exposure to damp and mould in private homesMethods: The study included a random sample of 50 000 inhabitants aged 16-50 in Telemark county, Norway. A total of 16 099 participated by returning a postal questionnaire collecting information about personal exposures and respiratory health. Exposure to damp and mould was defined as a positive response to: “Within the last 10 years, has there been any damp spots, water damage, or mould inside your home? ”Results: 3090 (19.6%) participants reported exposure to damp or mould at home. Among these, 1128 (37%) reported having atopy while 1895 (61%) were non-atopics, and 67 (2%) missing. Exposure to damp or mould in private homes was associated with increased odds ratio for respiratory symptoms and asthma, and these associations were stronger among non-atopics compared to atopics except for asthma and use of asthma medication



Conclusion: The results suggest a need for further investigation into non-allergic mechanisms responsible for respiratory symptoms and asthma that occur following exposure to damp or mould.


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Andre Amaral (London, United Kingdom), Andre Amaral, David Strachan, Francisco Gomez Real, Peter Burney, Deborah Jarvis. Lung function in postmenopausal women from the UK Biobank. Eur Respir J 2016; 48: Suppl. 60, 5001

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