Regulation of actin dynamics by WNT-5A: Implications for human airway smooth muscle contraction

Tim Koopmans (Groningen, Netherlands), Tim Koopmans, Kuldeep Kumawat, Andrew Halayko, Reinoud Gosens

Source: International Congress 2016 – Studies in airway cell biology
Session: Studies in airway cell biology
Session type: Thematic Poster
Number: 3986
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Tim Koopmans (Groningen, Netherlands), Tim Koopmans, Kuldeep Kumawat, Andrew Halayko, Reinoud Gosens. Regulation of actin dynamics by WNT-5A: Implications for human airway smooth muscle contraction. Eur Respir J 2016; 48: Suppl. 60, 3986

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
WNT-5A and WNT-11 as novel regulators of the contractile airway smooth muscle phenotype
Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Year: 2013


FGF-2 modulates human airway smooth muscle contractile protein expression and cell stiffness
Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Year: 2013

Airway smooth muscle contractility is increased following coculture with fibrocytes
Source: International Congress 2016 – Mechanisms of disease
Year: 2016

TGF-beta alters TRPC6 expression and calcium handling via smad2/3 in human airway smooth muscle
Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Year: 2013


Targeting ASK1 in preventing airway smooth muscle growth: Implications for airway remodeling in COPD
Source: International Congress 2016 – New findings in mucosal immunology
Year: 2016


MNK-1 inhibition reduces proliferation and CXCL10 in airway smooth muscle cells
Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Year: 2013

Link between airway inflammation and remodeling: TNFα induces airway smooth muscle cell proliferation via an ET1/GMCSF/IL6 network
Source: International Congress 2015 – Airway remodelling: recent developments
Year: 2015

Small-non coding YRNAs can regulate the plasticity of smooth muscle cells
Source: Annual Congress 2013 –Genetics and genomics of lung disease
Year: 2013

Integrins regulate eosinophil adhesion to the airway smooth muscle cells in asthma patients
Source: International Congress 2015 – Asthma mechanisms and management
Year: 2015

Extracellular matrix within the airway smooth muscle layer correlates with age but not in cases of asthma
Source: International Congress 2016 – Translational studies in lung disease
Year: 2016

Eosinophil-induced airway smooth muscle cells remodeling is attenuated by blocking of RGD-binding integrins in asthma
Source: International Congress 2016 – New findings in mucosal immunology
Year: 2016

A functional role for WNT-5A in driving airway myocyte proliferation
Source: Annual Congress 2013 –Growth factors at the crossroads of acute and chronic inflammation
Year: 2013


Epac1 and Epac2 regulate airway smooth muscle tone in mice
Source: International Congress 2016 – Translational studies in lung disease
Year: 2016

DP2/CRTh2 is expressed by ASM cells in asthma and its inhibition suppresses ASM migration
Source: International Congress 2016 – Mechanisms of disease
Year: 2016

Substrate stiffness and geometry differentially regulate proliferation in airway smooth muscle cells
Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Year: 2013

The role of glycolysis in TGF-beta-mediated airway smooth muscle cell proliferation
Source: International Congress 2014 – Cell biology 2014
Year: 2014

p53 dysfunction increased mitochondrial biogenesis and bronchial smooth muscle cell proliferation in asthma
Source: International Congress 2015 – Airway remodelling: recent developments
Year: 2015


CCL2 release by airway smooth muscle is increased in asthma and promotes fibrocyte migration
Source: International Congress 2014 – Cell biology 2014
Year: 2014


The effect of JQ1/SGCBD01 upon c-Myc in human airway smooth muscle in asthma
Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs
Year: 2014


The extracellular matrix deposited by asthmatic airway smooth muscle cells in a resting state reflects a healthy matrix
Source: International Congress 2015 – Airway remodelling: recent developments
Year: 2015