Source: Annual Congress 2001 - Monitoring acute lung disease
Disease area: Respiratory critical care

Abstract

The menagment of heavy burns poses very difficult problems of circulatory and respiratory insufficiency which need a reliable criteria for their monitoring.
In 37 severely burned patients were investigated the changes in the levels of blood lactate and P50 determined repeatedly in the course of the treatment together with the acid-base status and blood gases (gase analyzer NOVA - USA). Data were analysed with respect to the area of burn injury (below and above 30%) as well as the issue of the illness (51% survivors and 49% nonsurvivors). Elevated levels of lactate (above 2.0 mmol/l) were found in 44% of the patients (nonsurvivors - 3.83 ±] 2.68 mmol/l, survivors - 2.12 ±] 1.36 mmol/l, p<0,05). There is also statisticaly significant difference according to the burn area. For the canges in P50 (which gives information about the shape of the oxygen dissociation curve) we found that in the groups of patients with burns below 30% and survivors P50 is statisticaly lower in comparison with the groups with burns above 30% and nonsurvivors. The data were compared with acid-base status and blood gases. The determination of blood lactate and P50 gives useful information about tissue oxygen transport in patients with burn injury and can be a guide for their intensive treatment.

Rating:

Share or cite this content

Citations should be made in the following way:
M. Tsareva, A. Christova, S. Todorova (Sofia, Bulgaria). Significance of the monitoring of lactate and P50 for estimation of oxygen transport in burn patients. Eur Respir J 2001; 16: Suppl. 31, 1645

Member's Comments

No comment yet.

Related content which might interest you: Arterial oxygen content primarily reflects haemoglobin concentration in a cohort of hypoxaemic patients Source: International Congress 2016 – Clinical exercise physiology in health and disease Year: 2016 Is the initial stable value of transcutaneous oxygen/carbon dioxide monitoring equivalent to the blood gas values in oxygen assessments? Source: Eur Respir J 2007; 30: Suppl. 51, 181s Year: 2007 Remote monitoring of oxygen saturation in individuals with COVID-19 pneumonia Source: Eur Respir J, 56 (2) 2001492; 10.1183/13993003.01492-2020 Year: 2020 Poor agreement between haemoglobin oxygen saturation measured by pulse oximetry and arterialized earlobe blood gas in ambulatory paediatric sickle cell patients Source: International Congress 2016 – What's new in paediatric respiratory physiology? Year: 2016 Changes in circulating blood volume and some correlations with oxygen transport in patients with traumatic shock Source: Eur Respir J 2003; 22: Suppl. 45, 71s Year: 2003 Converting venous acid-base and oxygen status to arterial in patients with lung disease Source: Eur Respir J 2009; 33: 1141-1147 Year: 2009 Kinetics of haemoglobin oxygen saturation measured by continuous pulse oximetry during the 6 minute walking test Source: Annual Congress 2008 - Pulmonary rehabilitation for non-COPD and severe COPD; field exercise testing Year: 2008 Impact of automatic oxygen titration alone or with high flows on exercise tolerance in patients with lung disease and exercise oxygen desaturation Source: Virtual Congress 2020 – New insights into evaluation and treatment of respiratory disease Year: 2020 Monitoring carbon dioxide tension and arterial oxygen saturation using TOSCA monitoring in general respiratory ward Source: Eur Respir J 2006; 28: Suppl. 50, 394s Year: 2006 Relationship between blood potassium, hydrogen, lactate ions and pulmonary ventilation during different exercise testing protocols Source: Eur Respir J 2002; 20: Suppl. 38, 297s Year: 2002 Arterial lactate vs venous lactate as indicator of metabolic limitation during cardiopulmonary exercise testing. Source: International Congress 2018 – Respiratory physiology and measurements Year: 2018 Changes in the level of blood lactate in severely ill patients Source: Eur Respir J 2004; 24: Suppl. 48, 677s Year: 2004 Predicting arterial oxygen tension following inspired oxygen adjustment Source: Annual Congress 2010 - Acute respiratory failure Year: 2010 Reproducibility of resting oxygen uptake measurements and consequence for calculated cardiac output Source: Eur Respir J 2004; 24: Suppl. 48, 403s Year: 2004 The correlation of arterial oxygen saturation measured by pulse oxymeter and by arterial blood gas analyzer in patients with chronic respiratory failure Source: Eur Respir J 2005; 26: Suppl. 49, 526s Year: 2005 Multi-night continuous nocturnal oxygen saturation measurements in patients with COPD Source: International Congress 2018 – Functional assessment of COPD Year: 2018 High prolylhydroxylase oxygen sensors compensate for low oxygen supply Source: Lung Science Conference 2006 - Hypoxia in Lung Biology and Disease Year: 2006 Oxygen saturation index as a surrogate to oxygenation index in predicting outcomes in ARDS Source: Virtual Congress 2020 – Novel findings regarding acute respiratory distress syndrome, extra corporeal membrane oxygenation and weaning from mechanical ventilation Year: 2020 Relating oxygen partial pressure, saturation and content: the haemoglobin–oxygen dissociation curve Source: Breathe 2015; 11:194-201 Year: 2015 Oxygen uptake measured at the ventilatory threshold is a mortality marker in COPD Source: Virtual Congress 2020 – Exploring respiratory function Year: 2020