Source: International Congress 2016 – Pulmonary hypertension and pulmonary embolism: from the bench to the bedside
Disease area: Pulmonary vascular diseases, Respiratory critical care

Abstract

IntroductionElderly patients are at increased risk for pulmonary embolism (PE) and recurrence.AimTo define clinical characteristics of elderly PE patients and risk factors for recurrence.MethodWe retrospectively analysed PE patients aged 75 and over between 2010 and 2015.ResultsThere were 73 patients. Main risk factors for PE were:bedridden (24.6%), recent hospitalization (13.7%), active cancer (12.3%), recent surgery (5.4%) and previous deep vein thrombosis (DVT) history (6.8%). In hospital mortality was 2.7% (2 patients). One patient with previous multiple myeloma who was entubated due to respiratory failure and other patient died during catheter directed thrombolysis. Forty patients (56.3%) were discharged with warfarin, 30 (42.3%) with low molecular heparin and one with rivaroxaban. There wasn't any in hospital bleeding. After discharge 5 patients (6.8%) had bleeding (3 epistaxis, 1 hematuria and 1 gastrointestinal). Patient with gastrointestinal bleeding died. Others didn't need interventional procedures for bleeding. Eleven PE and 5 previous DVT total 16 (21.9%) venous thromboembolism (VTE) patients had recurrent PE. Statistically significant risk factors for recurrence were inadequate treatment of index VTE (p 0.048) and previous DVT history (p 0.048). Bedridden, recent hospitalization, comorbidities and discharge with warfarin or LMWH and treatment duration were not statistically significantly different between two groups.ConclusionDuration of anticoagulation should comply with guidelines. Prophylaxis with LMWH is mandatory for hospitalized patients with previous VTE history. Major bleeding risk is low and shouldn't be a reason for inadequate treatment or prophylaxis.


Rating:

Share or cite this content

Citations should be made in the following way:
Serhat Erol (Ankara, Turkey), Serhat Erol, Aslihan Gurun, Fatma Ciftci, Aydin Ciledag, Akin Kaya, Elif Sen, Gokhan Celik, Ismail Savas. Clinical characteristics of elderly patients with pulmonary embolism and risk factors for recurrence. Eur Respir J 2016; 48: Suppl. 60, 2493

Member's Comments

No comment yet.

Related content which might interest you: Clinical characteristics and prognostic factors of pulmonary embolism in different age groups Source: Annual Congress 2013 –Pulmonary circulation: acute pulmonary tromboembolism Year: 2013 Clinical profile and mortality of patients with pulmonary embolism and cancer Source: International Congress 2015 – Pulmonary circulation: the story of fresh and old clots Year: 2015 Evaluation of predictors of early and late mortality in 414 acute pulmonary embolism patients Source: International Congress 2016 – Pulmonary hypertension and pulmonary embolism: from the bench to the bedside Year: 2016 From CTPA-proven pulmonary embolism to patients clinical characteristics Source: Annual Congress 2013 –Pulmonary circulation: acute pulmonary tromboembolism Year: 2013 Clinical and prognostic scores in patients with cancer and pulmonary embolism Source: International Congress 2016 – Acute pulmonary embolism Year: 2016 Factors influencing mortality in ICU patients with suspected massive pulmonary embolism Source: International Congress 2016 – Infections, sepsis, and pulmonary embolism Year: 2016 Hemorrhagic complications of treatment in patients with pulmonary embolism Source: International Congress 2016 – Pulmonary hypertension and pulmonary embolism: from the bench to the bedside Year: 2016 Validation of a prognostic score for pulmonary embolism short-term mortality Source: International Congress 2015 – Pulmonary circulation: pulmonary embolism and chronic thromboembolic pulmonary hypertension Year: 2015 Late Breaking Abstract - Incidence, risk factors and thrombotic load of pulmonary embolism in patients hospitalized with COVID-19 Source: Virtual Congress 2021 – Insights into pulmonary embolism Year: 2021 Search predictive factors of recurrence in venous thromboembolic disease associated with cancer after withdrawal of the anticoagulation. HISPALIS study Source: International Congress 2016 – Acute pulmonary embolism Year: 2016 Do we ever learn? Risk stratification and investigation of suspected pulmonary embolism Source: Annual Congress 2013 –Pulmonary circulation: acute pulmonary tromboembolism Year: 2013 Recurrence patterns for venous thromboembolism - who is most at risk? Source: International Congress 2014 – Respiratory disease within hospital-based populations Year: 2014 Changes in PESI scores predict mortality in intermediate-risk patients with acute pulmonary embolism Source: Eur Respir J 2013; 41: 354-359 Year: 2013 Acute Pulmonary Embolism in COPD patients, clinical features and outcomes Source: International Congress 2017 – Pulmonary embolism Year: 2017 Pre-operative anaemia does not influence clinical outcome in patients undergoing pulmonary endarterectomy (PEA) Source: International Congress 2016 – Special issues in thoracic surgery Year: 2016 Characteristics of the patiens diagnosed with pulmonary thromboembolism in the last 10 years Source: Annual Congress 2013 –Pulmonary circulation: acute pulmonary tromboembolism Year: 2013 Relationship between pulmonary embolism severity index (PESI) score and unfavorable inpatient prognosis in non-high risk pulmonary embolism (PE) Source: International Congress 2016 – Acute pulmonary embolism Year: 2016 Electrocardiographic abnormalities in patients with low or moderate risk pulmonary embolism: Prevalence and association with PO2 /FiO2 ratio Source: International Congress 2014 – Acute pulmonary embolism Year: 2014 Do persistent perfusion defects predict late recurrences in pulmonary embolism? Source: International Congress 2014 – Acute pulmonary embolism Year: 2014 Risk stratification of pulmonary embolism: clinical evaluation, biomarkers or both? Source: Eur Respir J 2015; 46: 1551-1553 Year: 2015