MiR-185/AKT and miR-29a/collagen 1a pathways are activated in IPF alveolar macrophages

Katerina Antoniou (Heraklion, Crete, Greece), Eliza Tsitoura, Athol U. Wells, Chara Koutoulaki, Konstantinos Karagiannis, Ismini Lasithiotaki, Eirini Vasarmidi, Hiroe Sato, Demetrios A. Spandidos, Nikolaos M. Siafakas, Georgios Sourvinos, Katerina Antoniou

Source: International Congress 2016 – IPF: from pathogenesis to treatment II
Session: IPF: from pathogenesis to treatment II
Session type: Poster Discussion
Number: 2094
Disease area: Interstitial lung diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Katerina Antoniou (Heraklion, Crete, Greece), Eliza Tsitoura, Athol U. Wells, Chara Koutoulaki, Konstantinos Karagiannis, Ismini Lasithiotaki, Eirini Vasarmidi, Hiroe Sato, Demetrios A. Spandidos, Nikolaos M. Siafakas, Georgios Sourvinos, Katerina Antoniou. MiR-185/AKT and miR-29a/collagen 1a pathways are activated in IPF alveolar macrophages. Eur Respir J 2016; 48: Suppl. 60, 2094

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Expression of macrophage migration inhibitory factor in patients with idiopathic pulmonary fibrosis
Source: International Congress 2015 – Interstitial lung diseases II
Year: 2015

Role of macrophage activation in type II alveolar cells transplantation for the treatment of idiopathic pulmonary fibrosis
Source: Annual Congress 2013 –Translational studies in chronic repair and remodelling in the lung
Year: 2013


The RANKL-OPG balance in pulmonary fibrosis
Source: International Congress 2015 – Connective tissue disorders
Year: 2015

CFTR-dependent deficiency in alternatively-activated macrophages in cystic fibrosis
Source: International Congress 2016 – Cystic fibrosis: inflammation, microbiology, management and monitoring
Year: 2016


Pirfenidone suppresses proinflammatory and antiangiogenetic cytokine production by alveolar macrophages (AMs) in idiopathic non specific interstitial pneumonia (iNSIP)
Source: International Congress 2014 – ILDs 2
Year: 2014

Identification of profibrotic cells in the Idiopathic Pulmonary Fibrosis (IPF) lung
Source: Virtual Congress 2020 – Idiopathic pulmonary fibrosis and interstitial lung disease: progression, genes and more
Year: 2020

Characterization of M1 and M2 macrophages in human lung tissue
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013

Alveolar type II cells transplantation in pulmonary fibrosis: Effect on the lung macrophage activation
Source: Annual Congress 2013 –Translational studies in chronic repair and remodelling in the lung
Year: 2013


Impaired HGF-production by alveolar macrophages is a feature of diabetic pneumonia
Source: Annual Congress 2013 –The vulnerable patient and ageing cells
Year: 2013

Functional phenotype of immune response and alveolar macrophages phenotype in pulmonary sarcoidosis
Source: International Congress 2014 – New insights into monocyte and macrophage biology
Year: 2014


Mast cells and fibroblasts work in concert to aggravate pulmonary fibrosis: Role of transmembrane SCF and PAR-2/PKCalpha/Raf-1/p44/42 signaling pathway
Source: Annual Congress 2013 –Idiopathic pulmonary fibrosis and rarities
Year: 2013

Oxidative stress drives defective efferocytosis in COPD M2-like macrophages
Source: International Congress 2014 – New insights into monocyte and macrophage biology
Year: 2014

Induced pluripotent stem cells conditioned media (iPS-cm) modulates macrophage phenotype in the fibrotic lung
Source: International Congress 2014 – Lung cell biology in injury and repair
Year: 2014

Neutrophil chemotaxis and adhesion in patients with idiopathic pulmonary fibrosis (IPF)
Source: Eur Respir J 2001; 18: Suppl. 33, 108s
Year: 2001

Elevated GM-CSF in COPD may drive defective macrophage phenotype
Source: International Congress 2014 – New insights into monocyte and macrophage biology
Year: 2014

Pulmonary alveolar proteinosis: iPS derived macrophages as in-vitro disease model and potential source for novel gene and cell therapies
Source: Annual Congress 2013 –Preclinical models for the development of new drugs for respiratory diseases
Year: 2013

M2 polarized alveolar macrophages in pulmonary fibrosis
Source: Annual Congress 2005 - Pulmonary hypertension and fibrosis: novel mechanisms
Year: 2005


Increased apoptosis of alveolar lymphocytes (AL) in idiopathic pulmonary fibrosis (IPF). Potential mechanisms and practical considerations
Source: Annual Congress 2013 –Idiopathic pulmonary fibrosis: clinical view
Year: 2013


Clinical and functional features in idiopathic pulmonary fibrosis (IPF) with and without haemosiderin-laden alveolar macrophages on BALF
Source: Annual Congress 2011 - Bronchoalveolar lavage and biomarkers in diffuse parenchymal lung disease
Year: 2011

Impaired monocyte chemotaxis in COPD
Source: International Congress 2015 – Mucosal immunology: what’s new in 2015
Year: 2015