Source: International Congress 2016 – Best abstracts in physical activity and telemedicine
Disease area: Airway diseases

Abstract

Introduction: It has been estimated that 47% of people with COPD referred to pulmonary rehabilitation programs experience exercise-induced desaturation (EID) (nadir SpO2 < 90% during a six minute walk test (6MWT)). There is limited information available on exercise capacity and physical activity (PA) levels of this group.Aim: To determine whether there is a difference in functional exercise capacity and PA levels in people with COPD with EID and without EID.Methods: This was an observational study comparing outcomes in COPD people with and without EID. PA was assessed as the average of (i) number of steps per day, and (ii) time spent in sedentary (0 to <1.5 METs) and moderate activity (3 to <6 METs), using a multi-sensor accelerometer (SenseWear). 6MWT distance from the better of two 6MWTs was used to measure functional exercise capacity.Results: 65 participants were recruited to the EID group (mean (SD) age 70 (7) years, FEV1 50 (20) %predicted, nadir SpO2 84 (4)%) and 77 participants to the no EID group (age 69 (8), FEV1 48 (14) %predicted). Functional exercise capacity was lower in the EID group compared to the no EID group (6MWD 406 (97) m vs 479 (81) m, mean difference (95% CI) -73m (-43 to -102), p<0.01). PA levels were lower in the EID group compared to the no EID group with a lower average steps per day (2976 (2120) vs 5686 (2944), p<0.01), less time spent in moderate activity (23 (29) mins vs 50 (34) mins, p<0.01) and more time spent sedentary (19.7 (2) hrs vs 18.8 (2) hrs, p<0.05).Conclusion: Functional exercise capacity and PA levels were lower in people with COPD who had EID compared to those without EID, despite similar age and disease severity.


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Zoe McKeough (Sydney, Australia), Zoe McKeough, Regina Leung, Christine McDonald, Sue Jenkins, Anne Holland, Kylie Hill, Norman Morris, Catherine Hill, Annemarie Lee, Nola Cecins, Helen Seale, Lissa Spencer, Sally Wootton, Cindy Ng, Jennifer Alison. Exercise capacity and activity levels in people with COPD who experience exercise-induced oxygen desaturation. Eur Respir J 2016; 48: Suppl. 60, 2066

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